Ling Chunmei, Muyidouli Xiamusiye, Sulidan Adila, Muhetaer Abulimiti, Rejiafu Shawulaxi, Zhang Jun, Kulaixi Yilixiati, Abudousilimu Maidina, Masudan Paerman, Zhang Rong
Division for Chronic and Non-Communicable Disease Control and Prevention, The Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, China.
Sci Rep. 2025 May 23;15(1):17941. doi: 10.1038/s41598-025-01950-y.
To analyze the status and related risk factors of prediabetes, diabetes and diabetes control among adult residents in Xinjiang, so as to provide basis and guidance for local diabetes prevention and treatment. A multi-stage stratified sampling method was adopted to conduct preliminary screening of all residents aged 18 years old and above. Personal characteristics, blood glucose, hypertension and blood fat were collected by questionnaire survey, physical measurements and laboratory examinations respectively, and the risk factors of prediabetes, diabetes and blood glucose control were analyzed by binary logistic regression model. The prevalence of prediabetes and diabetes and the control rates of blood glucose in 2010 and 2018 were 17.47% and 20.13%, 12.27% and 15.43%, 35.05% and 38.82%, respectively. The increasing trend was found in prevalence of prediabetes and diabetes. Old age, marriage (including cohabitation), divorce (including separation), overweight or obesity, central obseity and dyslipidemia were risk factors in prediabetes, diabetes was related to old age, family history of diabetes, overweight and obesity, central obesity, hypertension and dyslipidemia, and diabetes blood glucose control was influenced by age, region, central obesity and dyslipidemia. Compared with 2010, the adverse effects on prediabetes of gender and diabetes of region were not significant, and the problem of impaired blood glucose caused by harmful drinking behavior was also alleviated. The prevalence of prediabetes and diabetes in Xinjiang residents is still at a high level, and the control of blood glucose needs to be further strengthened. Meanwhile, the elderly, region, married or divorced, family history of diabetes, overweight and obesity, central obesity, hypertension and dyslipidemia are the key groups for prevention and treatment of diabetes in this area. Active control of weight, blood pressure and blood lipids, screening and publicity of prediabetes and diabetes, and regular monitoring and early intervention are of great significance to reduce the incidence and adverse outcomes of diabetes.
分析新疆成年居民中糖尿病前期、糖尿病及糖尿病控制的现状和相关危险因素,为当地糖尿病防治提供依据和指导。采用多阶段分层抽样方法对所有18岁及以上居民进行初筛。分别通过问卷调查、体格测量和实验室检查收集个人特征、血糖、高血压和血脂情况,并采用二元逻辑回归模型分析糖尿病前期、糖尿病及血糖控制的危险因素。2010年和2018年糖尿病前期和糖尿病的患病率及血糖控制率分别为17.47%和20.13%、12.27%和15.43%、35.05%和38.82%。糖尿病前期和糖尿病患病率呈上升趋势。高龄、婚姻状况(包括同居)、离异(包括分居)、超重或肥胖、中心性肥胖和血脂异常是糖尿病前期的危险因素,糖尿病与高龄、糖尿病家族史、超重和肥胖、中心性肥胖、高血压和血脂异常有关,糖尿病血糖控制受年龄、地区、中心性肥胖和血脂异常影响。与2010年相比,性别对糖尿病前期及地区对糖尿病的不利影响不显著,有害饮酒行为导致的血糖受损问题也有所缓解。新疆居民糖尿病前期和糖尿病患病率仍处于较高水平,血糖控制有待进一步加强。同时,老年人、地区、已婚或离异、糖尿病家族史、超重和肥胖、中心性肥胖、高血压和血脂异常是该地区糖尿病防治的重点人群。积极控制体重、血压和血脂,筛查和宣传糖尿病前期和糖尿病,定期监测和早期干预对于降低糖尿病发病率和不良结局具有重要意义。