Zhou X, Guan H, Zheng L, Li Z, Guo X, Yang H, Yu S, Sun G, Li W, Hu W, Guo L, Pan G, Xing L, Zhang Y, Sun Y
Department of Cardiology, First Hospital of China Medical University, Shenyang, Liaoning, China.
Diabet Med. 2015 Mar;32(3):332-42. doi: 10.1111/dme.12599. Epub 2014 Dec 16.
To clarify the diabetes prevalence trends among the rural population in northern China.
All eligible permanent residents aged ≥ 35 years in selected rural villages of Liaoning province were invited to participate in the study. A total of 11 600 people completed all questionnaires and were included in the study. The response rate was 85.3%. Fasting plasma glucose levels were measured after at least 12 h of fasting and diabetes was diagnosed according to WHO criteria, i.e. fasting plasma glucose ≥ 7 mmol/l and/or being on treatment for diabetes. Impaired fasting glucose was defined according to the 1997 and the 2010 American Diabetes Association (ADA) criteria (6.1-6.9 and 5.6-6.9 mmol/l, respectively). Previous diagnoses of diabetes were assessed on the basis of self-reports.
The prevalence of diabetes among adults in the rural population was 10.6% (10.0% in men and 11.1% in women). The prevalence of impaired fasting glucose was 13.0 and 36.1% according to the 1997 and the 2010 ADA criteria, respectively. The prevalence of previously diagnosed diabetes was 4.3% among the whole population (3.3% in men and 5.1% in women). The prevalence of previously diagnosed diabetes was 34.8% in men and 50.2% in women. Only 29.6% of men and 42% of women with diabetes had taken oral hypoglycaemic agents or insulin to lower their blood sugar. In multivariate analysis, age, drinking habits, BMI, dyslipidaemia and family history of diabetes were identified as independent risk factors for diabetes, and occupational physical activity, smoking and lean meat intake were identified as independent protective factors for diabetes.
The prevalence of diabetes and impaired fasting glucose were found to be high in this rural population. Although the rate of treatment of people with diabetes has increased, the glycaemic control rate was still at a low level.
明确中国北方农村人口中的糖尿病患病率趋势。
邀请辽宁省选定农村村庄中所有年龄≥35岁的符合条件的常住居民参与研究。共有11600人完成所有问卷并纳入研究。应答率为85.3%。空腹至少12小时后测量空腹血糖水平,并根据世界卫生组织标准诊断糖尿病,即空腹血糖≥7 mmol/l和/或正在接受糖尿病治疗。空腹血糖受损根据1997年和2010年美国糖尿病协会(ADA)标准定义(分别为6.1 - 6.9和5.6 - 6.9 mmol/l)。既往糖尿病诊断根据自我报告进行评估。
农村人口中成年人糖尿病患病率为10.6%(男性为10.0%,女性为11.1%)。根据1997年和2010年ADA标准,空腹血糖受损患病率分别为13.0%和36.1%。在整个人口中,既往诊断糖尿病的患病率为4.3%(男性为3.3%,女性为5.1%)。既往诊断糖尿病的患者中,男性为34.8%,女性为50.2%。只有29.6%的男性糖尿病患者和42%的女性糖尿病患者服用过口服降糖药或胰岛素来降低血糖。多因素分析中,年龄、饮酒习惯、体重指数、血脂异常和糖尿病家族史被确定为糖尿病的独立危险因素,职业体力活动、吸烟和瘦肉摄入量被确定为糖尿病的独立保护因素。
在该农村人口中发现糖尿病和空腹血糖受损的患病率较高。尽管糖尿病患者的治疗率有所提高,但血糖控制率仍处于较低水平。