Ferroni Matthew, Taylor Aisha Khalali
Department of Urology, University of Pittsburgh Medical Center, 300 Halket Street, Suite 4710, Pittsburgh, PA 15213, USA.
Department of Urology, University of Pittsburgh Medical Center, 300 Halket Street, Suite 4710, Pittsburgh, PA 15213, USA.
Urol Clin North Am. 2015 Nov;42(4):537-45. doi: 10.1016/j.ucl.2015.07.003. Epub 2015 Aug 11.
Asymptomatic bacteriuria (ASB) is a common finding and frequently detected in premenopausal nonpregnant women, institutionalized patients, patients with diabetes mellitus, and the ambulatory elderly population. Despite clear recommendations regarding diagnosis and management of ASB in these populations from the Infectious Diseases Society of America (IDSA), there remains an alarming rate of antimicrobial overuse. This article reviews definitions of ASB, epidemiology of ASB, literature surrounding ASB in diabetic patients, risk factors of ASB, microbiologic data regarding bacterial virulence, use of ASB strains for treatment of symptomatic urinary tract infection, and approaches to addressing translational barriers to implementing IDSA recommendations regarding diagnosis and management of ASB.
无症状菌尿(ASB)是一种常见现象,在绝经前非妊娠女性、机构化患者、糖尿病患者及老年门诊人群中经常被检测到。尽管美国传染病学会(IDSA)针对这些人群中ASB的诊断和管理给出了明确建议,但抗菌药物过度使用的比例仍然高得惊人。本文综述了ASB的定义、ASB的流行病学、糖尿病患者中ASB的相关文献、ASB的危险因素、关于细菌毒力的微生物学数据、使用ASB菌株治疗有症状尿路感染以及解决实施IDSA关于ASB诊断和管理建议的转化障碍的方法。