利用 Humphrey 24-2 视野检查预测 Humphrey 10-2 视野检查中旁中心暗点存在的临床线索
Clinical Clues to Predict the Presence of Parafoveal Scotoma on Humphrey 10-2 Visual Field Using a Humphrey 24-2 Visual Field.
作者信息
Park Hae-Young Lopilly, Hwang Bo-Een, Shin Hye-Young, Park Chan Kee
机构信息
Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Seoul St Mary's Hospital, Seoul, South Korea.
Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Uijeongbu St Mary's Hospital, Uijeongbu, South Korea.
出版信息
Am J Ophthalmol. 2016 Jan;161:150-9. doi: 10.1016/j.ajo.2015.10.007. Epub 2015 Oct 22.
PURPOSE
To investigate characteristics related to the presence of parafoveal scotoma on Humphrey 10-2 visual field (VF) in early glaucoma patients.
DESIGN
Prospective, cross-sectional study.
METHODS
participants: Ninety-one eyes from 91 patients with glaucomatous optic neuropathy were prospectively tested with a 10-2 VF test.
OBSERVATION PROCEDURES
Glaucoma patients were classified into eyes with or without parafoveal scotoma on 10-2 VF based on pattern deviation plot. The central 10 degree region of Humphrey 24-2 VF test comprised 12 points and any abnormal VF points depressed <5%, <2%, <1%, or <0.5% from the normal database on pattern deviation plot were analyzed. Various factors related to the presence of parafoveal scotoma on 10-2 VF were analyzed.
MAIN OUTCOME MEASURES
Abnormal 24-2 VF points, macular ganglion cell-inner plexiform layer thickness.
RESULTS
The presence of abnormal 24-2 VF points <0.5% was significantly different between eyes with and without parafoveal scotoma on 10-2 VF (P < .01). The minimum macular ganglion cell-inner plexiform layer thickness (P = .04), any central 12 points depressed <0.5% on 24-2 VF (P < .01), and any central 12 points depressed <5% on 24-2 VF that spatially corresponds to macular ganglion cell-inner plexiform layer thinning (P < 0.01) were related factors to the presence of parafoveal scotoma on 10-2 VF.
CONCLUSIONS
Glaucomatous eyes with any abnormal 24-2 VF points on the central 10 degree region that are depressed <0.5% or <5% that correlates to macular ganglion cell-inner plexiform layer thinning should receive attention and be further evaluated with a 10-2 VF test.
目的
研究早期青光眼患者 Humphrey 10 - 2 视野（VF）中旁中心暗点存在相关的特征。
设计
前瞻性横断面研究。
方法
参与者：对 91 例青光眼性视神经病变患者的 91 只眼睛进行前瞻性 10 - 2 VF 测试。
观察程序
根据模式偏差图，将青光眼患者分为 10 - 2 VF 有或无旁中心暗点的眼睛。Humphrey 24 - 2 VF 测试的中央 10 度区域包括 12 个点，分析模式偏差图上偏离正常数据库<5%、<2%、<1%或<0.5%的任何异常 VF 点。分析与 10 - 2 VF 上旁中心暗点存在相关的各种因素。
主要观察指标
异常的 24 - 2 VF 点、黄斑神经节细胞 - 内丛状层厚度。
结果
10 - 2 VF 有或无旁中心暗点的眼睛之间，24 - 2 VF 点异常<0.5%的情况有显著差异（P <.01）。最小黄斑神经节细胞 - 内丛状层厚度（P =.04）、24 - 2 VF 上任何中央 12 个点压低<0.5%（P <.01）以及 24 - 2 VF 上任何中央 12 个点压低<5%且在空间上对应于黄斑神经节细胞 - 内丛状层变薄（P < 0.01）是 10 - 2 VF 上旁中心暗点存在的相关因素。
结论
在中央 10 度区域有任何异常的 24 - 2 VF 点且压低<0.5%或<5%且与黄斑神经节细胞 - 内丛状层变薄相关的青光眼性眼睛应予以关注，并进一步进行 10 - 2 VF 测试评估。
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