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阴茎香豆素坏死

Coumarin necrosis of the penis.

作者信息

Barkley C, Badalament R A, Metz E N, Nesbitt J, Drago J R

机构信息

Department of Surgery, Ohio State University, Columbus.

出版信息

J Urol. 1989 Apr;141(4):946-8. doi: 10.1016/s0022-5347(17)41064-0.

DOI:10.1016/s0022-5347(17)41064-0
PMID:2648033
Abstract

Coumarin-induced necrosis of the skin and subcutaneous tissue is an uncommon but well recognized complication of anticoagulant therapy. Although any area of skin may be involved necrosis of the penis is rare. We report a case of penile necrosis associated with coumarin therapy and review the literature.

摘要

香豆素诱导的皮肤和皮下组织坏死是抗凝治疗中一种罕见但已被充分认识的并发症。虽然皮肤的任何部位都可能受累,但阴茎坏死却很罕见。我们报告一例与香豆素治疗相关的阴茎坏死病例并复习相关文献。

相似文献

1
Coumarin necrosis of the penis.阴茎香豆素坏死
J Urol. 1989 Apr;141(4):946-8. doi: 10.1016/s0022-5347(17)41064-0.
2
A case of coumarin necrosis with penile and pedal involvement.一例累及阴茎和足部的香豆素坏死病例。
J Eur Acad Dermatol Venereol. 1998 May;10(3):248-52.
3
[Coumarin necrosis (author's transl)].[香豆素坏死(作者译)]
Zentralbl Chir. 1979;104(11):713-7.
4
Recurrent thromboembolism, disseminated intravascular coagulation, and coumarin-induced skin necrosis associated with protein C deficiency.
Pathol Res Pract. 1988 Jun;183(3):308-13. doi: 10.1016/S0344-0338(88)80127-4.
5
Heterozygous protein C deficiency and coumarin necrosis of the skin.
Rom J Intern Med. 1992 Apr-Jun;30(2):105-11.
6
Soft tissue necrosis and gangrene complicating treatment with the coumarin derivatives.香豆素衍生物治疗引发的软组织坏死和坏疽
Surg Gynecol Obstet. 1977 Oct;145(4):497-500.
7
Recurrent coumarin-induced skin necrosis in a patient with an acquired functional protein C deficiency.
Arch Dermatol. 1986 Dec;122(12):1408-12.
8
[Coumarin-induced necrosis--a rare complication of oral anticoagulant therapy].[香豆素诱导的坏死——口服抗凝治疗的一种罕见并发症]
Chirurgia (Bucur). 2010 Jul-Aug;105(4):559-62.
9
Coumarin skin necrosis complicating thrombophlebitis and pulmonary emboli: case report.香豆素类药物致皮肤坏死并发血栓性静脉炎和肺栓塞:病例报告
Am Surg. 1972 Aug;38(8):451-3.
10
Treatment of coumarin-induced skin necrosis with a monoclonal antibody purified protein C concentrate.用单克隆抗体纯化蛋白C浓缩物治疗香豆素诱导的皮肤坏死。
Arch Dermatol. 1993 Jun;129(6):753-6.

引用本文的文献

1
Warfarin-induced skin necrosis: a narrative review of clinical features, risk factors, and treatment strategies.华法林所致皮肤坏死:临床特征、危险因素及治疗策略的叙述性综述
Ann Med Surg (Lond). 2025 Sep 12;87(11):7249-7260. doi: 10.1097/MS9.0000000000003848. eCollection 2025 Nov.
2
Skin Necrosis Induced by Coumarin Congeners.香豆素类同系物诱导的皮肤坏死
Tex Heart Inst J. 2017 Aug 1;44(4):233-236. doi: 10.14503/THIJ-17-6430. eCollection 2017 Aug.
3
Extensive warfarin-induced skin necrosis successfully treated with negative pressure wound therapy.
广泛华法林诱导的皮肤坏死经负压伤口治疗成功治愈。
BMJ Case Rep. 2014 Apr 17;2014:bcr2013203510. doi: 10.1136/bcr-2013-203510.
4
Warfarin-induced penile necrosis in a patient with heparin-induced thrombocytopenia.华法林诱导伴肝素诱导血小板减少症患者阴茎坏死。
J Korean Med Sci. 2010 Sep;25(9):1390-3. doi: 10.3346/jkms.2010.25.9.1390. Epub 2010 Aug 16.
5
Coumarin-induced skin necrosis. Incidence, mechanisms, management and avoidance.
Drug Saf. 1993 Feb;8(2):128-35. doi: 10.2165/00002018-199308020-00003.