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地中海饮食队列中的勃起功能障碍与心血管危险因素

Erectile dysfunction and cardiovascular risk factors in a Mediterranean diet cohort.

作者信息

Ramírez R, Pedro-Botet J, García M, Corbella E, Merino J, Zambón D, Corbella X, Pintó X

出版信息

Intern Med J. 2016 Jan;46(1):52-6. doi: 10.1111/imj.12937.

Abstract

BACKGROUND

Erectile dysfunction affects more than 100 million men worldwide, with a wide variability in prevalence. An overall association of cardiovascular risk factors, lifestyle and diet in the context of ED in a Mediterranean population is lacking.

AIM

To assess ED prevalence and associated factors in a Mediterranean cohort of non-diabetic patients with cardiovascular risk factors.

METHODS

Observational, cross-sectional study of patients aged over 40 treated at cardiovascular risk units in Catalonia. Anthropometric data, risk factors, lifestyle and diet habits were recorded. ED was assessed using the International Index of Erectile Function.

RESULTS

Four hundred and forty patients included, 186 (42.3%) with ED (24.8% mild, 6.8% moderate and 10.7% severe). ED presence and severity were associated with age, obesity, waist circumference, hypertension, antihypertensive treatment and ischaemic disease. Patients with ED were more frequently smokers, sedentary and consumed more alcohol. In multivariate analysis, consumption of nuts (> twice a week) (OR 0.41 (95% CI 0.25 to 0.67) and vegetables (≥ once a day) (OR 0.47 (95% CI 0.28-0,77)), were inversely related to ED. Obesity (as BMI ≥ 30 kg/m(2) ) (OR 2.49 (95% CI 1.48-4.17)), ischaemic disease (OR 2.30 (95% CI 1.22 to 4.33), alcohol consumption (alcohol-units a day) (OR 1.14 (95% CI 1.04 to 1.26), and age (year) (OR = 1.07 (95% CI 1.04-1.10) were directly related to ED.

CONCLUSION

Erectile dysfunction is a common disorder in patients treated in lipid units in Catalonia for cardiovascular risk factors. This condition is associated with age, obesity, ischaemic disease and unhealthy lifestyle habits.

摘要

背景

全球超过1亿男性患有勃起功能障碍,患病率差异很大。在地中海人群中,缺乏心血管危险因素、生活方式和饮食与勃起功能障碍之间的总体关联。

目的

评估地中海地区有心血管危险因素的非糖尿病患者队列中勃起功能障碍的患病率及相关因素。

方法

对加泰罗尼亚心血管风险单位治疗的40岁以上患者进行观察性横断面研究。记录人体测量数据、危险因素、生活方式和饮食习惯。使用国际勃起功能指数评估勃起功能障碍。

结果

纳入440例患者,186例(42.3%)患有勃起功能障碍(轻度24.8%,中度6.8%,重度10.7%)。勃起功能障碍的存在和严重程度与年龄、肥胖、腰围、高血压、抗高血压治疗和缺血性疾病有关。勃起功能障碍患者吸烟、久坐和饮酒更为频繁。多因素分析中,每周食用坚果超过两次(比值比0.41(95%可信区间0.25至0.67))和每天食用蔬菜至少一次(比值比0.47(95%可信区间0.28至0.77))与勃起功能障碍呈负相关。肥胖(体重指数≥30kg/m²)(比值比2.49(95%可信区间1.48至4.17))、缺血性疾病(比值比2.30(95%可信区间1.22至4.33))、饮酒量(每天酒精单位)(比值比1.14(95%可信区间1.04至1.26))和年龄(岁)(比值比=1.07(95%可信区间1.04至1.10))与勃起功能障碍呈正相关。

结论

在加泰罗尼亚因心血管危险因素在血脂单位接受治疗的患者中,勃起功能障碍是一种常见疾病。这种情况与年龄、肥胖、缺血性疾病和不健康的生活习惯有关。

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