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直肠癌手术后的排尿功能障碍

URINARY DYSFUNCTION AFTER SURGICAL TREATMENT FOR RECTAL CANCER.

作者信息

Beraldo Fernando Bray, Yusuf Sonia Ahlaim Ibrahim, Palma Rogério Tadeu, Kharmandayan Silvia, Gonçalves José Eduardo, Waisberg Jaques

机构信息

Serviço de Gastroenterologia Cirúrgica, Hospital do Servidor Público Estadual de São Paulo, São Paulo, SP, BR.

Departamento de Cirurgia, Faculdade de Medicina do ABC, Santo André, SP, BR.

出版信息

Arq Gastroenterol. 2015 Jul-Sep;52(3):180-5. doi: 10.1590/S0004-28032015000300005.

Abstract

BACKGROUND

The impact on quality of life attributed to treatment for rectal cancer remains high. Deterioration of the urinary function is a relevant complication within that context.

OBJECTIVE

To detect the presence of urinary dysfunction and its risk factors among individuals underwent surgical treatment for rectal cancer.

METHODS

The present prospective study analyzed 42 patients from both genders underwent surgical treatment for rectal adenocarcinoma with curative intent. The version of the International Prostatic Symptom Score (IPSS) questionnaire validated for the Portuguese language was applied at two time-points: immediately before and 6 months after surgery. Risk factors for urinary dysfunction were analysed by means of logistic regression and Student's t-test.

RESULTS

Eight (19%) participants exhibited moderate-to-severe urinary dysfunction 6 months after surgery; the average IPSS increased from 1.43 at baseline to 4.62 six months after surgery (P<0.001). None of the variables assessed as potential risk factors exhibited statistical significance, i.e., age, gender, distance from tumour to anal margin, neoadjuvant therapy, adjuvant therapy, type of surgery, surgical approach (laparoscopy or laparotomy), and duration of surgery.

CONCLUSION

This study identified an incidence of 19% of moderate to severe urinary dysfunction after 6 months surveillance. No risk factor for urinary dysfunction was identified in this population.

摘要

背景

直肠癌治疗对生活质量的影响仍然很大。在这种情况下,泌尿功能恶化是一种相关并发症。

目的

检测接受直肠癌手术治疗的个体中是否存在泌尿功能障碍及其危险因素。

方法

本前瞻性研究分析了42例接受根治性手术治疗直肠腺癌的患者,男女均有。在两个时间点应用了经葡萄牙语验证的国际前列腺症状评分(IPSS)问卷版本:手术前即刻和手术后6个月。通过逻辑回归和学生t检验分析泌尿功能障碍的危险因素。

结果

8名(19%)参与者在术后6个月出现中度至重度泌尿功能障碍;IPSS平均值从基线时的1.43增加到术后6个月的4.62(P<0.001)。作为潜在危险因素评估的变量均无统计学意义,即年龄、性别、肿瘤距肛缘距离、新辅助治疗、辅助治疗、手术类型、手术入路(腹腔镜或开腹手术)和手术持续时间。

结论

本研究发现,在6个月的监测后,中度至重度泌尿功能障碍的发生率为19%。在该人群中未发现泌尿功能障碍的危险因素。

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