Keene H J, Shklair I L, Mickel G J, Wirthlin M R
J Dent Res. 1977 Jan;56(1):5-10. doi: 10.1177/00220345770560011101.
The distribution of S mutans biotypes in five geographically separated human populations was investigated. Samples of dental plaque were obtained from recruits at the US Naval Training Center in Orlando, Fl (N=49) in San Diego, Calif (N=25), and in Great Lakes, Ill (N=194), and from a sample of Hawaiian school children (N=55) and Saudi Arabian Navy personnel (N-217). Cultural and biochemical methods were used for the isolation and identification of the five different biotypes of S mutans which correlate with Bratthall's serotypes a through e. Geographic differences in S mutans biotype distribution were most apparent when the Saudi Arabian sample was compared to the other four groups. Single and multiple biotypes were observed in each group. Multiple biotypes occurred most frequently in the Saudi Arabians. Biotypes a and b were rarely observed; c was the most common in each of the populations; and d and e were more prevalent in the Saudi Arabians than in the other groups. Because of the multifactorial nature of dental caries, caution should be exercised in the interpretation of population differences in caries experience that seem to be associated with differences in S mutans-type distribution.
研究了变形链球菌生物型在五个地理上分离的人群中的分布情况。从佛罗里达州奥兰多市美国海军训练中心的新兵（N = 49）、加利福尼亚州圣地亚哥市的新兵（N = 25）、伊利诺伊州五大湖地区的新兵（N = 194）、一组夏威夷学龄儿童（N = 55）以及沙特阿拉伯海军人员（N = 217）中获取牙菌斑样本。采用培养和生化方法分离并鉴定了与布拉特霍尔血清型a至e相关的五种不同生物型的变形链球菌。当将沙特阿拉伯的样本与其他四组进行比较时，变形链球菌生物型分布的地理差异最为明显。每组中均观察到单一生物型和多种生物型。多种生物型在沙特阿拉伯人中出现的频率最高。生物型a和b很少被观察到；生物型c在每个人群中都是最常见的；生物型d和e在沙特阿拉伯人中比在其他组中更为普遍。由于龋齿具有多因素性质，在解释似乎与变形链球菌型分布差异相关的人群龋齿经历差异时应谨慎。
