Munkhaugen John, Sverre Elise, Peersen Kari, Gjertsen Erik, Gullestad Lars, Moum Torbjorn, Otterstad Jan Erik, Perk Joep, Husebye Einar, Dammen Toril
a Department of Medicine , Drammen Hospital , Drammen , Norway ;
b Department of Medicine , Vestfold Hospital , Tønsberg , Norway ;
Scand Cardiovasc J. 2016;50(1):1-8. doi: 10.3109/14017431.2015.1111408. Epub 2015 Nov 17.
This project aims to identify socio-demographic, medical and psychosocial factors (study factors) associated with coronary risk control and prognosis, and to test their impact in a representative sample of coronary heart disease (CHD) patients.
The first phase includes a cross-sectional study designed to explore the association between the study factors and coronary risk factor control in CHD patients. Data from hospital records, a questionnaire, clinical examination and blood samples were collected. The independent effects of study factors on subsequent coronary events will be explored prospectively by controlling for baseline coronary risk factors. In the second phase, we will test the effect of tailored interventions to modify the study factors associated with unfavourable risk profile in phase I.
In all 1366 patients (21% women), aged 18-80 years with a coronary event on average 17 (2-38) months prior to study participation were identified (83% participation rate). Of the 239 patients who refused participation, 229 patients consented to analysis of hospital record data (non- participants).
If the study variables contribute to CHD risk factors and prognosis, the present project may be important for the development of prevention programs by tailoring these to the patients perceived needs and behaviour profiles.
本项目旨在确定与冠心病风险控制及预后相关的社会人口学、医学和心理社会因素(研究因素),并在冠心病(CHD)患者的代表性样本中检验其影响。
第一阶段包括一项横断面研究,旨在探究研究因素与冠心病患者冠心病危险因素控制之间的关联。收集了来自医院记录、问卷、临床检查和血液样本的数据。通过控制基线冠心病危险因素,前瞻性地探究研究因素对后续冠心病事件的独立影响。在第二阶段,我们将测试针对性干预措施的效果,以改变在第一阶段中与不良风险状况相关的研究因素。
共纳入1366例患者(21%为女性),年龄在18至80岁之间,平均在参与研究前17(2 - 38)个月发生过冠心病事件(参与率83%)。在239例拒绝参与的患者中,229例同意对医院记录数据进行分析(非参与者)。
如果研究变量对冠心病危险因素和预后有影响,那么本项目通过根据患者的感知需求和行为特征进行定制,可能对预防方案的制定具有重要意义。