Suppr超能文献

可行、高效且必要,无一例外——与性工作者合作可阻断艾滋病毒/性传播感染的传播,并为众多有需要的人带来治疗。

Feasible, Efficient and Necessary, without Exception - Working with Sex Workers Interrupts HIV/STI Transmission and Brings Treatment to Many in Need.

作者信息

Steen Richard, Wheeler Tisha, Gorgens Marelize, Mziray Elizabeth, Dallabetta Gina

机构信息

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Office of HIV/AIDS, United States Agency for International Development, Washington, District of Columbia, United States of America.

出版信息

PLoS One. 2015 Oct 21;10(10):e0121145. doi: 10.1371/journal.pone.0121145. eCollection 2015.

Abstract

BACKGROUND AND OVERVIEW

High rates of partner change in sex work-whether in professional, 'transactional' or other context-disproportionately drive transmission of HIV and other sexually transmitted infections. Several countries in Asia have demonstrated that reducing transmission in sex work can reverse established epidemics among sex workers, their clients and the general population. Experience and emerging research from Africa reaffirms unprotected sex work to be a key driver of sexual transmission in different contexts and regardless of stage or classification of HIV epidemic. This validation of the epidemiology behind sexual transmission carries an urgent imperative to realign prevention resources and scale up effective targeted interventions in sex work settings, and, given declining HIV resources, to do so efficiently. Eighteen articles in this issue highlight the importance and feasibility of such interventions under four themes: 1) epidemiology, data needs and modelling of sex work in generalised epidemics; 2) implementation science addressing practical aspects of intervention scale-up; 3) community mobilisation and 4) the treatment cascade for sex workers living with HIV.

CONCLUSION

Decades of empirical evidence, extended by analyses in this collection, argue that protecting sex work is, without exception, feasible and necessary for controlling HIV/STI epidemics. In addition, the disproportionate burden of HIV borne by sex workers calls for facilitated access to ART, care and support. The imperative for Africa is rapid scale-up of targeted prevention and treatment, facilitated by policies and action to improve conditions where sex work takes place. The opportunity is a wealth of accumulated experience working with sex workers in diverse settings, which can be tapped to make up for lost time. Elsewhere, even in countries with strong interventions and services for sex workers, an emerging challenge is to find ways to sustain them in the face of declining global resources.

摘要

背景与概述

性工作中伴侣更换率高——无论是在专业、“交易性”还是其他背景下——都在很大程度上推动了艾滋病毒和其他性传播感染的传播。亚洲的几个国家已经证明,减少性工作中的传播可以扭转性工作者、其客户和普通人群中已有的疫情。非洲的经验和新出现的研究再次证实,无保护的性工作是不同背景下性传播的关键驱动因素,且与艾滋病毒疫情的阶段或分类无关。对性传播背后流行病学的这种确认迫切需要重新调整预防资源,并在性工作场所扩大有效的针对性干预措施,而且鉴于艾滋病毒资源不断减少,要高效地做到这一点。本期的18篇文章在四个主题下突出了此类干预措施的重要性和可行性:1)在广泛流行中的性工作流行病学、数据需求和建模;2)解决干预措施扩大规模实际问题的实施科学;3)社区动员;4)艾滋病毒感染性工作者的治疗级联。

结论

数十年的实证证据,加上本论文集的分析,表明毫无例外,保护性工作对于控制艾滋病毒/性传播感染疫情是可行且必要的。此外,性工作者承担的艾滋病毒不成比例的负担要求为其提供更多获得抗逆转录病毒治疗、护理和支持的机会。非洲的当务之急是迅速扩大针对性预防和治疗,通过改善性工作发生环境的政策和行动来推动。机会在于在不同环境中与性工作者合作积累的丰富经验,可以利用这些经验来弥补失去的时间。在其他地方,即使在对性工作者有强有力干预措施和服务的国家,一个新出现的挑战是在全球资源减少的情况下找到维持这些措施的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6ee/4619404/28921bd8091d/pone.0121145.g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验