高强度间歇训练与中等强度训练对改善超重或肥胖男性心血管代谢健康的影响：一项随机对照试验
High Intensity Interval- vs Moderate Intensity- Training for Improving Cardiometabolic Health in Overweight or Obese Males: A Randomized Controlled Trial.
作者信息
Fisher Gordon, Brown Andrew W, Bohan Brown Michelle M, Alcorn Amy, Noles Corey, Winwood Leah, Resuehr Holly, George Brandon, Jeansonne Madeline M, Allison David B
机构信息
Department of Human Studies, University of Alabama at Birmingham, Birmingham, AL, United States of America; Nutrition and Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, United States of America; Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Nutrition and Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL, United States of America; Office of Energetics, University of Alabama at Birmingham, Birmingham, AL, United States of America.
出版信息
PLoS One. 2015 Oct 21;10(10):e0138853. doi: 10.1371/journal.pone.0138853. eCollection 2015.
PURPOSE
To compare the effects of six weeks of high intensity interval training (HIIT) vs continuous moderate intensity training (MIT) for improving body composition, insulin sensitivity (SI), blood pressure, blood lipids, and cardiovascular fitness in a cohort of sedentary overweight or obese young men. We hypothesized that HIIT would result in similar improvements in body composition, cardiovascular fitness, blood lipids, and SI as compared to the MIT group, despite requiring only one hour of activity per week compared to five hours per week for the MIT group.
METHODS
28 sedentary overweight or obese men (age, 20 ± 1.5 years, body mass index 29.5 ± 3.3 kg/m2) participated in a six week exercise treatment. Participants were randomly assigned to HIIT or MIT and evaluated at baseline and post-training. DXA was used to assess body composition, graded treadmill exercise test to measure cardiovascular fitness, oral glucose tolerance to measure SI, nuclear magnetic resonance spectroscopy to assess lipoprotein particles, and automatic auscultation to measure blood pressure.
RESULTS
A greater improvement in VO2peak was observed in MIT compared to HIIT (11.1% vs 2.83%, P = 0.0185) in the complete-case analysis. No differences were seen in the intention to treat analysis, and no other group differences were observed. Both exercise conditions were associated with temporal improvements in % body fat, total cholesterol, medium VLDL, medium HDL, triglycerides, SI, and VO2peak (P < 0.05).
CONCLUSION
Participation in HIIT or MIT exercise training displayed: 1) improved SI, 2) reduced blood lipids, 3) decreased % body fat, and 4) improved cardiovascular fitness. While both exercise groups led to similar improvements for most cardiometabolic risk factors assessed, MIT led to a greater improvement in overall cardiovascular fitness. Overall, these observations suggest that a relatively short duration of either HIIT or MIT training may improve cardiometabolic risk factors in previously sedentary overweight or obese young men, with no clear advantage between these two specific regimes (Clinical Trial Registry number NCT01935323).
TRIAL REGISTRATION
ClinicalTrials.gov NCT01935323.
目的
比较六周高强度间歇训练（HIIT）与持续中等强度训练（MIT）对改善久坐不动的超重或肥胖年轻男性队列的身体成分、胰岛素敏感性（SI）、血压、血脂和心血管健康状况的效果。我们假设，与MIT组相比，HIIT尽管每周只需一小时的运动，而MIT组每周需要五小时，但在身体成分、心血管健康、血脂和SI方面会带来相似的改善。
方法
28名久坐不动的超重或肥胖男性（年龄20±1.5岁，体重指数29.5±3.3kg/m²）参加了为期六周的运动治疗。参与者被随机分配到HIIT或MIT组，并在基线和训练后进行评估。使用双能X线吸收法（DXA）评估身体成分，分级平板运动试验测量心血管健康状况，口服葡萄糖耐量试验测量SI，核磁共振波谱法评估脂蛋白颗粒，自动听诊法测量血压。
结果
在完整病例分析中，与HIIT相比，MIT组的最大摄氧量（VO₂peak）有更大改善（11.1%对2.83%，P = 0.0185）。在意向性分析中未发现差异，也未观察到其他组间差异。两种运动条件均与体脂百分比、总胆固醇、中密度极低密度脂蛋白（VLDL）、中密度高密度脂蛋白（HDL）、甘油三酯、SI和VO₂peak的时间性改善相关（P < 0.05）。
结论
参与HIIT或MIT运动训练显示：（1）SI改善；（2）血脂降低；（3）体脂百分比降低；（4）心血管健康改善。虽然两个运动组对大多数评估的心血管代谢危险因素都带来了相似的改善，但MIT组在整体心血管健康方面有更大改善。总体而言，这些观察结果表明，相对较短时间的HIIT或MIT训练可能改善既往久坐不动的超重或肥胖年轻男性的心血管代谢危险因素，这两种特定训练方案之间没有明显优势（临床试验注册号NCT01935323）。
试验注册
ClinicalTrials.gov NCT01935323。
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