Programa de Pós-Graduação em Educação Física, Centro de Educação Física e Esportes, Universidade Federal do Mato Grosso, Cuiabá, MT, Brasil.
Programa de Pós-Graduação em Ciências em Saúde (PPGCS), Universidade Federal do Mato Grosso, Campus Universitário de Sinop, Sinop, MT, Brasil.
Braz J Med Biol Res. 2024 Nov 4;57:e13676. doi: 10.1590/1414-431X2024e13676. eCollection 2024.
High-intensity interval training (HIIT) has stood out as a treatment for obesity, leading to adaptations of the cardiovascular system and reducing body adiposity. In addition, the search for alternative therapies for weight loss has intensified. The administration of Hibiscus sabdariffa (Hs) has been described as an efficient supplement in weight loss and in the treatment of metabolic changes associated with obesity. In this context, the objective was to investigate the effects of the association of Hs and HIIT on metabolic adaptations and lipid metabolism in obese rats. Wistars rats were subjected to obesity and subsequently randomized into 4 groups: obese (Ob), obese + HS (ObHs), obese + HIIT (ObHIIT), and obese + HS + HIIT (ObHsHIIT). For 8 weeks, ObHs and ObHsHIIT rats received Hs extract daily (150 mg/kg of body weight) and trained groups (ObHIIT and ObHsHIIT) were subjected to a HIIT program on a treadmill. Nutritional profile, glycemic curve, biochemical profile, and liver glycogen were determined. HIIT decreased caloric intake, feed efficiency, body adiposity, total body fat, and body weight gain, associated with improvements in physical performance parameters and a smaller glycemic curve and area. Hs had a hepatoprotective effect, reducing alkaline phosphatase values, but its effects were more pronounced when associated with HIIT. Therefore, the combination of treatments promoted a reduction in food consumption and body adiposity, as well as an improvement in physical performance and glycemic profile, but without changes in lipid metabolism.
高强度间歇训练（HIIT）在治疗肥胖方面表现出色，导致心血管系统适应和减少身体脂肪。此外，寻找减肥的替代疗法的需求也在增加。服用洛神花（Hs）已被描述为减肥和治疗与肥胖相关的代谢变化的有效补充剂。在这种情况下，目的是研究 Hs 与 HIIT 联合对肥胖大鼠代谢适应和脂代谢的影响。Wistars 大鼠被诱发肥胖，随后随机分为 4 组：肥胖组（Ob）、肥胖+HS 组（ObHs）、肥胖+HIIT 组（ObHIIT）和肥胖+HS+HIIT 组（ObHsHIIT）。8 周内，ObHs 和 ObHsHIIT 组大鼠每天接受 Hs 提取物（150mg/kg 体重），并对运动组（ObHIIT 和 ObHsHIIT）进行跑步机 HIIT 训练。测定营养状况、血糖曲线、生化指标和肝糖原。HIIT 减少了热量摄入、饲料效率、身体脂肪、总脂肪和体重增加，同时改善了身体表现参数，降低了血糖曲线和面积。Hs 具有肝保护作用，降低碱性磷酸酶值，但与 HIIT 联合使用时效果更为明显。因此，联合治疗可减少食物摄入和身体脂肪，改善身体表现和血糖状况，但对脂代谢没有影响。
