Arena Ansotegui J, Emparanza Knörr J I, San Millán Vege M J, Garrido Chércoles A, Eguileor Gurtubai I
Departamento de Pediatría, Hospital Nuestra Señora Aranzazu, San Sebastián.
An Esp Pediatr. 1989 Jan;30(1):23-6.
The high incidence of transient thyroid dysfunction in newborns from our hospital (0.6%), led us to investigate whether povidone perineal prep. during delivery and daily postpartum antisepsis, induced iodine overload in the newborn, and whether breast milk was the vehiccle. In a controlled randomized trial we used either povidone-iodine or clorhexidine in 36 mothers, and we investigated in them and in their newborns iodine levels and thyroid function. Iodine levels in cord blood, maternal urine and newborn urine were significantly higher in povidone treated group (p less than 0.001) up to the 4th postpartum day. These levels were also significantly higher in breast fed than in formula-fed babies within the group of povidone-iodine-treated mothers. Maternal prepartum urine iodine, and thyroid function in mothers and newborns were not significantly different in both groups.
我院新生儿短暂性甲状腺功能障碍的高发病率（0.6%），促使我们研究分娩时聚维酮会阴准备以及产后每日进行的消毒是否会导致新生儿碘摄入过量，以及母乳是否为碘摄入过量的载体。在一项对照随机试验中，我们对36名母亲分别使用聚维酮碘或氯己定，并对她们及其新生儿的碘水平和甲状腺功能进行了研究。在产后第4天之前，聚维酮治疗组脐带血、母体尿液和新生儿尿液中的碘水平显著更高（p<0.001）。在聚维酮碘治疗的母亲组中，母乳喂养的婴儿的这些水平也显著高于配方奶喂养的婴儿。两组母亲的产前尿碘以及母亲和新生儿的甲状腺功能均无显著差异。
