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小脑肿瘤切除术后的短暂性缄默症。一例病例报告及文献综述。

Transient mutism following removal of a cerebellar tumor. A case report and review of the literature.

作者信息

Ammirati M, Mirzai S, Samii M

机构信息

Neurosurgical Clinic, Nordstadt Krankenhaus, Hannover, Federal Republic of Germany.

出版信息

Childs Nerv Syst. 1989 Feb;5(1):12-4. doi: 10.1007/BF00706739.

DOI:10.1007/BF00706739
PMID:2649239
Abstract

A 14-year-old boy developed mutism 24 h after the removal of a vermian low-grade astrocytoma. The mutism was not accompanied by long tract signs or cranial nerve palsies. He started to regain his speech 3 weeks postoperatively, and 4 months after the operation he was minimally dysarthric. Seven similar cases of transient muteness following cerebellar operations and not accompanied by long tract signs or cranial nerve palsies have been reported in the literature. In most of them there was delayed postoperative onset of the mutism. In all patients the recovery of speech started to appear 2 weeks to 3 months postoperatively and passed through a dysarthric phase. The absence of long tract or other brain stem signs, together with the presence of dysarthria during the recovery of speech, suggests a cerebellar cause for the transient muteness.

摘要

一名14岁男孩在切除小脑蚓部低级别星形细胞瘤后24小时出现缄默症。该缄默症未伴有长束征或脑神经麻痹。他在术后3周开始恢复说话,术后4个月时仅有轻微构音障碍。文献中已报道了7例类似的小脑手术后短暂缄默症病例,且均未伴有长束征或脑神经麻痹。其中大多数病例缄默症在术后延迟出现。所有患者的言语恢复在术后2周 至3个月开始出现,并经历了构音障碍阶段。缺乏长束征或其他脑干体征,以及在言语恢复过程中存在构音障碍,提示小脑是导致短暂缄默症的原因。

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本文引用的文献

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Pseudobulbar palsy after posterior fossa operation in children.儿童后颅窝手术后的假性延髓麻痹
Neurosurgery. 1984 Nov;15(5):707-9. doi: 10.1227/00006123-198411000-00014.
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Muteness of cerebellar origin.小脑源性缄默症。
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A case of muteness of cerebellar origin.一例小脑源性缄默症病例。
Cerebellar Mutism Syndrome following Midline Posterior Fossa Tumor Resection in Children: An Institutional Experience.
儿童后颅窝中线肿瘤切除术后的小脑缄默综合征:一项机构经验
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Cerebellum. 2011 Sep;10(3):551-62. doi: 10.1007/s12311-011-0273-2.
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