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皇家眼科医学院白内障手术全国眼科数据库研究:报告2,眼轴长度与眼部合并病变、术前视力及后囊破裂的关系

The Royal College of Ophthalmologists' National Ophthalmology Database Study of cataract surgery: report 2, relationships of axial length with ocular copathology, preoperative visual acuity, and posterior capsule rupture.

作者信息

Day A C, Donachie P H J, Sparrow J M, Johnston R L

机构信息

The NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.

The Royal College of Ophthalmologists' National Ophthalmology Database, Euston, London, UK.

出版信息

Eye (Lond). 2015 Dec;29(12):1528-37. doi: 10.1038/eye.2015.198. Epub 2015 Oct 23.

Abstract

PURPOSE

To describe the relationships of axial length with ocular copathology, preoperative visual acuity, and posterior capsule rupture rates in patients undergoing cataract surgery.DesignThe Royal College of Ophthalmologists' National Ophthalmology Database (NOD) study.

METHODS

Anonymised data on 180 114 eyes from 127 685 patients undergoing cataract surgery between August 2006 and November 2010 were collected prospectively from 28 sites. Data parameters included: demographics, biometry, ocular copathology, visual acuity measurements, and surgical complications including posterior capsule rupture, or vitreous loss or both (PCR).

RESULTS

Consultant surgeons performed a higher proportion of operations on eyes whose axial length were at the extremes. Glaucoma and age related macular degeneration were more common in eyes with shorter axial lengths, whilst previous vitrectomy was associated with longer axial lengths. Eyes with brunescent or white cataracts or amblyopia were more common at both axial length extremes. Preoperative visual acuities were similar for eyes with axial length measurements up to approximately 28 mm and worse for eyes with longer axial length measurements. PCR rates showed little change with axial length (overall mean 1.95%, 95% CI: 1.89 to 2.01%), except for a borderline increase in eyes with axial length <20.0 mm where rates were 3.6% (95% CI: 2.0 to 6.3%). The likelihood of PCR in eyes with axial length <20.0 mm was 1.88 times higher than those of ≥20.0 mm (P=0.0373).

CONCLUSION

Rates of ocular comorbidities vary by axial length. PCR rates in eyes with very short or long axial lengths were lower than expected.

摘要

目的

描述白内障手术患者眼轴长度与眼部合并病变、术前视力及后囊膜破裂率之间的关系。

设计

皇家眼科医师学院国家眼科数据库(NOD)研究。

方法

前瞻性收集2006年8月至2010年11月期间来自28个地点的127685例白内障手术患者的180114只眼的匿名数据。数据参数包括:人口统计学、生物测量学、眼部合并病变、视力测量以及手术并发症,包括后囊膜破裂、玻璃体丢失或两者皆有(后囊膜破裂)。

结果

顾问外科医生对眼轴长度处于极端值的眼睛进行手术的比例更高。青光眼和年龄相关性黄斑变性在眼轴较短的眼睛中更为常见,而既往玻璃体切除术与眼轴较长相关。在眼轴长度的两个极端,棕色或白色白内障或弱视的眼睛更为常见。眼轴长度测量值达约28mm的眼睛术前视力相似,而眼轴长度测量值较长的眼睛术前视力较差。后囊膜破裂率随眼轴长度变化不大(总体平均1.95%,95%可信区间:1.89%至2.01%),但眼轴长度<20.0mm的眼睛后囊膜破裂率略有增加,为3.6%(95%可信区间:2.0%至6.3%)。眼轴长度<20.0mm的眼睛发生后囊膜破裂的可能性比眼轴长度≥20.0mm的眼睛高1.88倍(P=0.0373)。

结论

眼部合并症的发生率因眼轴长度而异。眼轴极短或极长的眼睛后囊膜破裂率低于预期。

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