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超声乳化白内障吸除手术中眼轴长度对视力结果和并发症的影响:一项多中心数据库研究。

Impact of axial length on visual outcomes and complications in phacoemulsification surgery: a multicenter database study.

机构信息

Jones Eye Institute, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR, 72207, USA.

Department of Ophthalmology, Faculty of Medicine, Assiut University, Assiut, Egypt.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2023 Dec;261(12):3511-3520. doi: 10.1007/s00417-023-06120-2. Epub 2023 Jun 22.

Abstract

PURPOSE

To analyze the impact of axial length (AL) on the visual outcome and rate of perioperative complications in phacoemulsification surgery.

DESIGN

Retrospective clinical database study.

METHODS

Cataract surgery data of 217,556 eyes was extracted from the electronic medical records of 8 ophthalmic centers in the United Kingdom from July 2003 to March 2015. A total of 88,774 eyes without ocular co-pathologies were grouped eyes according to AL (mm): short AL (< 22), average AL (22-26; reference group), and long AL (> 26).

MAIN OUTCOMES AND MEASURES

We analyzed visual acuity (VA) outcomes at 4 weeks, 4-12 weeks, and 12-24 weeks postoperatively, as well as the incidence of posterior capsular rupture (PCR), torn iris (TI), cystoid macular edema (CME), and retinal detachment (RD).

RESULTS

Mean pre-operative VA (logMAR) was the worst in eyes with long AL compared to average and short AL eyes (VA 0.59 vs. 0.58 and 0.56; p < 0.001). However, post-operative VA at 4-12 weeks was slightly better in the long AL group (0.14 in short and average AL; 0.12 in long AL, p < 0.001). We observed an increased odds of TI in the short AL group (OR 2.09, 95% CI 1.60-2.75). There was increased risk of RD in long AL eyes (p < 0.001). However, PCR and CME rates were not different.

CONCLUSION

In the absence of any coexisting ocular pathology, AL alone did not have an impact on VA improvement or the risk of encountering PCR or CME. The risk of TI was greater in the short AL group, and the risk of RD was higher in the long AL group.

摘要

目的

分析眼轴(AL)长度对超声乳化白内障吸除术后视力结果和围手术期并发症发生率的影响。

设计

回顾性临床数据库研究。

方法

从 2003 年 7 月至 2015 年 3 月,从英国 8 家眼科中心的电子病历中提取了 217556 只眼的白内障手术数据。根据 AL(mm)将无眼部合并症的 88774 只眼分为短眼轴组(<22)、平均眼轴组(22-26;参考组)和长眼轴组(>26)。

主要观察指标

分析术后 4 周、4-12 周和 12-24 周的视力(VA)结果,以及后囊膜破裂(PCR)、虹膜撕裂(TI)、囊样黄斑水肿(CME)和视网膜脱离(RD)的发生率。

结果

与平均眼轴和短眼轴组相比,长眼轴组的术前平均 VA(logMAR)最差(VA 0.59 与 0.58 和 0.56;p<0.001)。然而,长眼轴组术后 4-12 周的 VA 稍好(短眼轴和平均眼轴组为 0.14;长眼轴组为 0.12,p<0.001)。我们发现短眼轴组 TI 的发生几率增加(OR 2.09,95%CI 1.60-2.75)。长眼轴组发生 RD 的风险增加(p<0.001)。然而,PCR 和 CME 发生率没有差异。

结论

在没有任何共存眼部疾病的情况下,仅眼轴长度本身不会影响 VA 改善或发生 PCR 或 CME 的风险。短眼轴组 TI 的风险更大,长眼轴组 RD 的风险更高。

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