Parissopoulos Stelios, Mpouzika Meropi DA, Timmins Fiona
Department of Nursing, Technological Educational Institute (T.E.I.) of Athens, Egaleo, Greece.
School of Nursing, Cyprus University of Technology, Limassol, Cyprus.
Nurs Crit Care. 2017 Jan;22(1):40-51. doi: 10.1111/nicc.12205. Epub 2015 Oct 23.
Adult respiratory distress syndrome (ARDS) is a type of acute diffuse lung injury characterized by severe inflammation, increased pulmonary vascular permeability and a loss of aerated lung tissue. The effects of high fraction of inspired oxygen (FiO ) include oxygen toxicity manifested by damage to the lung parenchyma in the acute phase of lung injury. There is still a high mortality rate among this group of patients, so clinically sensitive evidence-based interventions are paramount to maximize survival chances during critical care.
The aim of this article is to explore the current opinion concerning optimal mechanical ventilation support techniques for patients with acute respiratory distress syndrome.
SEARCH STRATEGY, INCLUSION AND EXCLUSION CRITERIA: A literature search of clinical trials and observation studies, reviews, discussion papers, meta-analyses and clinical guidelines written in English up to 2015, derived from the databases of Scopus, CINAHL, Cochrane Library databases and PubMed was conducted.
Low tidal volume, pressure limitation and prone positioning in severe ARDS patients appear to be of some benefit. More research is required and further development and use of standardized protocols is an important strategy for reducing practice variations across disciplines, as well as giving clear guidelines to nurses practising in critical care. There is also evidence that this syndrome is under-diagnosed and the utilization of lung protective ventilation is still variable.
It is important that nurses have underlying knowledge of both aetiology of ARDS and ventilation management, and that they monitor patients very closely. The adoption of a low tidal ventilation protocol, which is based on quality evidence guidelines, the value of rescue therapies and patient observation practices in the overall patient management, and the need to place emphasis on long-term patient outcomes, all these emerge as key factors for consideration and future research. However, there is also a need for more research that would explore the unique contribution of nurses in the management of this patient group, as it is difficult to discern this in the current literature.
成人呼吸窘迫综合征(ARDS)是一种急性弥漫性肺损伤,其特征为严重炎症、肺血管通透性增加以及充气肺组织丧失。高吸入氧分数(FiO)的影响包括在肺损伤急性期表现为肺实质损伤的氧中毒。该组患者的死亡率仍然很高,因此临床敏感的循证干预措施对于在重症监护期间最大限度地提高生存几率至关重要。
本文旨在探讨关于急性呼吸窘迫综合征患者最佳机械通气支持技术的当前观点。
检索策略、纳入和排除标准:对截至2015年以英文撰写的临床试验、观察性研究、综述、讨论论文、荟萃分析和临床指南进行文献检索,检索来源于Scopus、CINAHL、Cochrane图书馆数据库和PubMed数据库。
对于重症ARDS患者,低潮气量、压力限制和俯卧位似乎有一定益处。需要更多研究,进一步制定和使用标准化方案是减少各学科实践差异以及为重症监护护士提供明确指导的重要策略。也有证据表明该综合征诊断不足,肺保护性通气的应用仍然存在差异。
护士了解ARDS的病因和通气管理基础知识并密切监测患者非常重要。采用基于高质量循证指南的低潮气量通气方案、抢救治疗的价值以及患者观察实践在整体患者管理中的作用,以及强调患者长期预后的必要性,所有这些都是需要考虑和未来研究的关键因素。然而,也需要更多研究来探索护士在该患者群体管理中的独特贡献,因为在当前文献中难以辨别这一点。