Inoue Takuya, Misago Noriyuki, Asami Akihiko, Tokunaga Osamu, Narisawa Yutaka
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Department of Orthopedic Surgery, Japan Community Health-care Organization, Saga Central Hospital, Saga, Japan.
J Dermatol. 2016 May;43(5):557-9. doi: 10.1111/1346-8138.13161. Epub 2015 Oct 26.
We herein describe a case of myopericytoma that proliferated in an unusual fashion. Myopericytoma is described as a group of rare, benign, dermal or subcutaneous tumors that are characterized histologically by a striking, concentric, perivascular proliferation of spindle cells and showing apparent differentiation towards perivascular myoid cells. Myopericytoma forms a morphological continuum with myofibroma/myofibromatosis, glomus tumor and angioleiomyoma. The patient was a 64-year-old woman who demonstrated a recurrent ulcer on an atrophic plaque on her left shin. A histopathological examination of the plaque demonstrated that tumor cells proliferated in an anastomosing multinodular fashion along the vessels in the dermis and subcutaneous tissue. In those nodules, there were numerous, small, concentric proliferations of myoid-appearing spindle cells around small vascular lumina. The present case is an unusual example of myopericytoma, manifesting in a characteristic anastomosing, multinodular, infiltrating fashion.
我们在此描述一例以不寻常方式增殖的肌周细胞瘤。肌周细胞瘤被描述为一组罕见的良性真皮或皮下肿瘤，其组织学特征是梭形细胞呈显著的同心性血管周围增殖，并向血管周围肌样细胞明显分化。肌周细胞瘤与肌纤维瘤/肌纤维瘤病、血管球瘤和血管平滑肌瘤形成形态学连续谱。患者为一名64岁女性，其左小腿萎缩斑块上有复发性溃疡。对该斑块进行组织病理学检查显示，肿瘤细胞沿真皮和皮下组织中的血管以吻合性多结节方式增殖。在这些结节中，小血管腔周围有许多呈肌样的梭形细胞同心性小增殖。本病例是肌周细胞瘤的一个不寻常例子，以特征性的吻合性、多结节性、浸润性方式表现。
