Ahmed Hena, Field Wesley, Hayes Michael T, Lopez William Omar Contreras, McDannold Nathan, Mukundan Srinivasan, Tierney Travis S
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, USA.
Department of Neurology, South Shore Hospital, 55 Fogg Road, Weymouth, MA 02190, USA.
Magn Reson Imaging Clin N Am. 2015 Nov;23(4):515-22. doi: 10.1016/j.mric.2015.05.008. Epub 2015 Jul 11.
Progressively less invasive neurosurgical approaches for the treatment of movement disorders have evolved, beginning with open craniotomy for placement of lesions within pyramidal structures followed by refined stereotactic ablation of extrapyramidal targets that encouraged nondestructive electrode stimulation of deep brain structures. A noninvasive approach using transcranial high-energy focused ultrasound has emerged for the treatment of intractable tremor. The ability to target discreet intracranial sites millimeters in size through the intact skull using focused acoustic energy marks an important milestone in movement disorders surgery. This article describes the evolution of magnetic resonance-guided focused ultrasound for ventrolateral thalamotomy for tremor.
用于治疗运动障碍的侵入性越来越小的神经外科手术方法不断发展，最初是通过开颅手术在锥体结构内放置病灶，随后是对锥体外系靶点进行精细的立体定向消融，这促使了对深部脑结构进行非破坏性电极刺激。一种使用经颅高能聚焦超声的非侵入性方法已出现用于治疗顽固性震颤。利用聚焦声能通过完整颅骨靶向精确至毫米大小的颅内位点的能力，标志着运动障碍手术的一个重要里程碑。本文描述了磁共振引导聚焦超声用于震颤的腹外侧丘脑切开术的发展历程。
