The purine path to chemotherapy.
作者信息
Elion G B
机构信息
Wellcome Research Laboratories, Burroughs Wellcome Company, Research Triangle Park, NC 27709.
出版信息
Science. 1989 Apr 7;244(4900):41-7. doi: 10.1126/science.2649979.
PMID:2649979
Abstract
Research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia (6-mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine).
摘要
Zotero 插件