Liu Tao, Zhang Songya, Li Zhanlin, Wang Yu, Chen Zaixing, Bai Jiao, Tian Li, Pei Yuehu, Hua Huiming
a Department of Natural Products Chemistry, School of Pharmacy , China Medical University , Shenyang , China.
b Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University , Shenyang , China.
Nat Prod Res. 2016;30(9):1025-9. doi: 10.1080/14786419.2015.1101693. Epub 2015 Oct 23.
A new polyketide, penicillolide (1) was isolated from the fermentation broth of the marine-derived fungus Penicillium sacculum GT-308. Compound 1 is a polyketide with a unique carbon skeleton. The structure of this compound was established via extensive spectroscopic analyses including 1D-, 2D-NMR, and HRESI-MS.
从海洋来源的真菌青霉GT-308的发酵液中分离出一种新的聚酮化合物——青霉内酯(1)。化合物1是一种具有独特碳骨架的聚酮化合物。该化合物的结构通过包括一维、二维核磁共振以及高分辨电喷雾电离质谱在内的广泛光谱分析得以确定。