School of Psychiatry, University of New South Wales, Sydney, NSW, Australia; Early Psychosis Programme, The Bondi Centre, South Eastern Sydney Local Health District, Australia; Musculoskeletal Division, The George Institute for Global Health and School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
UPC KU Leuven, Campus Kortenberg, KU Leuven - University of Leuven, Department of Neurosciences, Kortenberg, Belgium; KU Leuven-University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.
Psychiatry Res. 2015 Dec 15;230(2):130-6. doi: 10.1016/j.psychres.2015.10.017. Epub 2015 Oct 20.
People with PTSD experience high levels of cardiovascular disease and comorbid mental health problems. Physical activity (PA) is an effective intervention in the general population. We conducted the first systematic review and meta-analysis to determine the effect of PA on PTSD. We searched major electronic databases from inception till 03/2015 for RCTs of PA interventions among people with PTSD. A random effects meta-analysis calculating hedges g was conducted. From a potential of 812 hits, four unique RCTs met the inclusion criteria (n=200, mean age of participants 34-52 years). The methodological quality of included trials was satisfactory, and no major adverse events were reported. PA was significantly more effective compared to control conditions at decreasing PTSD and depressive symptoms among people with PTSD. There was insufficient data to investigate the effect on anthropometric or cardiometabolic outcomes. Results suggest that PA may be a useful adjunct to usual care to improve the health of people with PTSD. Although there is a relative paucity of data, there is reason to be optimistic for including PA as an intervention for people with PTSD, particularly given the overwhelming evidence of the benefits of PA in the general population. Robust effectiveness and implementation studies are required.
创伤后应激障碍患者存在较高水平的心血管疾病和合并精神健康问题。身体活动（PA）是普通人群中一种有效的干预措施。我们进行了首次系统评价和荟萃分析，以确定 PA 对 PTSD 的影响。我们从建库起至 2015 年 3 月，在 PTSD 患者中检索了 PA 干预的随机对照试验（RCT）的主要电子数据库。采用计算 Hedge g 的随机效应荟萃分析。在 812 个潜在结果中，有 4 项独特的 RCT 符合纳入标准（n=200，参与者的平均年龄为 34-52 岁）。纳入试验的方法学质量令人满意，且未报告重大不良事件。与对照组相比，PA 在降低 PTSD 和抑郁症状方面对 PTSD 患者更有效。由于数据不足，无法调查对人体测量或心血管代谢结果的影响。结果表明，PA 可能是 PTSD 患者常规护理的有益辅助手段，可改善其健康状况。虽然数据相对较少，但有理由对将 PA 作为 PTSD 患者的干预措施持乐观态度，尤其是考虑到 PA 在普通人群中带来的益处的压倒性证据。需要进行更有效的研究和实施研究。
