Lysosomal acid lipase in cancer.
作者信息
Yan Cong, Zhao Ting, Du Hong
机构信息
Department of Pathology and Laboratory Medicine and IU Simon Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA.
出版信息
Oncoscience. 2015 Aug 30;2(9):727-8. doi: 10.18632/oncoscience.223. eCollection 2015.
Abstract
摘要
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本文引用的文献
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Myeloid-derived suppressor cells are involved in lysosomal acid lipase deficiency-induced endothelial cell dysfunctions.髓源性抑制细胞参与溶酶体酸性脂肪酶缺乏诱导的内皮细胞功能障碍。
J Immunol. 2014 Aug 15;193(4):1942-53. doi: 10.4049/jimmunol.1301941. Epub 2014 Jul 7.
2
Activation of mTOR pathway in myeloid-derived suppressor cells stimulates cancer cell proliferation and metastasis in lal(-/-) mice.髓源性抑制细胞中mTOR通路的激活会刺激lal(-/-)小鼠的癌细胞增殖和转移。
Oncogene. 2015 Apr 9;34(15):1938-48. doi: 10.1038/onc.2014.143. Epub 2014 Jun 2.
3
Critical role of the mTOR pathway in development and function of myeloid-derived suppressor cells in lal-/- mice.mTOR 通路在 lal-/- 小鼠髓系来源抑制细胞的发育和功能中的关键作用。
Am J Pathol. 2014 Feb;184(2):397-408. doi: 10.1016/j.ajpath.2013.10.015. Epub 2013 Nov 26.
4
Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.溶酶体酸性脂肪酶敲除小鼠骨髓中髓源性抑制细胞的基因谱。
PLoS One. 2012;7(2):e30701. doi: 10.1371/journal.pone.0030701. Epub 2012 Feb 27.
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Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis.在髓系细胞中抑制 PPARγ 会诱导全身性炎症、免疫抑制和肿瘤发生。
Blood. 2012 Jan 5;119(1):115-26. doi: 10.1182/blood-2011-06-363093. Epub 2011 Nov 3.
6
Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice.人溶酶体酸性脂肪酶在髓系细胞中的特异性表达纠正了 lal-/- 小鼠中髓源性抑制细胞的畸形和功能障碍。
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Critical roles of lysosomal acid lipase in T cell development and function.溶酶体酸性脂肪酶在T细胞发育和功能中的关键作用。
Am J Pathol. 2009 Mar;174(3):944-56. doi: 10.2353/ajpath.2009.080562. Epub 2009 Jan 29.
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