Vimercati Luigi, Gatti Maria Franca, Baldassarre Antonio, Nettis Eustachio, Favia Nicola, Palma Marco, Martina Gabriella Lucia Maria, Di Leo Elisabetta, Musti Marina
Interdisciplinary Department of Medicine, Occupational Medicine "B. Ramazzini", University of Bari Medical School, Bari 70124, Italy.
Department of Internal Medicine and Infectious Diseases, University of Bari Medical School, Bari 70124, Italy.
Int J Environ Res Public Health. 2015 Oct 16;12(10):12977-87. doi: 10.3390/ijerph121012977.
Exposure to air pollution is associated with increased morbidity from cardiovascular diseases, lung cancer, respiratory and allergic diseases. The aim of this study was to investigate allergic diseases in 111 traffic wardens compared to a control group of 101 administrative employees. All participating subjects underwent a physical examination, in which a complete medical history was taken and a dedicated allergological questionnaire administered. Spirometry, Specific IgE dosage (RAST) and skin prick tests (SPT) were done. Diagnostic investigations such as the nasal cytology, a specific nasal provocation test and rhinomanometry were also performed. Statistical analyses were performed using STATA version 11. The percentage of subjects with a diagnosis of allergy was higher in the exposed workers than in the controls. As regards the clinical tests, the positivity was higher for the group of exposed subjects. Among the exposed workers, those who worked on foot or motorcycle had a higher positivity in clinical trials compared to the traffic wardens who used the car. Our study showed a higher percentage of allergic subjects in the group of workers exposed to outdoor pollutants than in the controls. These results suggest that allergological tests should be included in the health surveillance protocols for workers exposed to outdoor pollutants.
暴露于空气污染与心血管疾病、肺癌、呼吸道和过敏性疾病的发病率增加有关。本研究的目的是调查111名交通协管员与101名行政雇员对照组相比的过敏性疾病情况。所有参与的受试者都接受了体格检查,包括采集完整的病史并进行专门的过敏学问卷调查。进行了肺活量测定、特异性IgE剂量测定(RAST)和皮肤点刺试验(SPT)。还进行了鼻细胞学检查、特异性鼻激发试验和鼻阻力测量等诊断性检查。使用STATA 11版进行统计分析。暴露组中被诊断为过敏的受试者百分比高于对照组。关于临床试验,暴露组的阳性率更高。在暴露组工人中,步行或骑摩托车工作的人在临床试验中的阳性率高于使用汽车的交通协管员。我们的研究表明,暴露于室外污染物的工人群体中过敏受试者的百分比高于对照组。这些结果表明,过敏学检测应纳入暴露于室外污染物的工人的健康监测方案中。