纳米颗粒：锌纳米颗粒对海洋甲壳类动物的毒性的实验研究。对人类健康影响的综合概述。

Nanoparticles: An Experimental Study of Zinc Nanoparticles Toxicity on Marine Crustaceans. General Overview on the Health Implications in Humans.

机构信息

Unit of Occupational Medicine, Interdisciplinary Department of Medicine (DIM), School of Medicine, University Hospital "Policlinico", University of Bari "A. Moro", Bari, Italy.

Marine Environment and Pollution Prevention, Department of Prevention, ASL TA Health Company, Taranto, Italy.

出版信息

Front Public Health. 2020 May 21;8:192. doi: 10.3389/fpubh.2020.00192. eCollection 2020.

DOI:10.3389/fpubh.2020.00192

PMID:32509719

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7253631/

Abstract

The presence of products containing nanoparticles or nanofibers is rapidly growing. Nanotechnology involves a wide spectrum of industrial fields. There is a lack of information regarding the toxicity of these nanoparticles in aqueous media. The potential acute toxicity of ZnO NPs using two marine crustacean species: the copepod and the amphypod was evaluated. Acute tests were conducted on adults of nauplii and . Both test species were exposed for 96 h to 5 increasing concentrations of ZnO NPs and ZnSOHO, and the endpoint was mortality. Statistical analysis revealed that the mean LC50 values of both ZnO NPs and ZnSOHO (ZnO NPs: = 59.42; < 0.0015; ZnSOHO: = 25.57; < 0.0015) were significantly lower for than for . This result confirms that the toxic effect could be mainly attributed to the Zn ions, confirming that the dissolution processes play a crucial role in the toxicity of the ZnO NPs.

摘要

纳米颗粒或纳米纤维产品的存在迅速增加。纳米技术涉及广泛的工业领域。关于这些纳米颗粒在水介质中的毒性的信息缺乏。使用两种海洋甲壳类动物：桡足类和端足类，评估了 ZnO NPs 的潜在急性毒性。对和的成年幼虫进行了急性试验。这两种试验物种都在 5 个不断增加的 ZnO NPs 和 ZnSOHO 浓度下暴露 96 小时，终点是死亡率。统计分析显示，两种 ZnO NPs 和 ZnSOHO（ZnO NPs： = 59.42；<0.0015；ZnSOHO： = 25.57；<0.0015）的平均 LC50 值对均显著低于对。这一结果证实，毒性效应主要归因于 Zn 离子，证实了溶解过程在 ZnO NPs 的毒性中起着关键作用。