Stavem P, Berg K, Noer G
Scand J Haematol. 1977 Jan;18(1):13-9. doi: 10.1111/j.1600-0609.1977.tb01472.x.
Serum leukaemia associated antigen (LAA) was found in 41-75% of patients with acute leukaemia or chronic myelogenous leukaemia, but in only 12% of persons suffering from chronic lymphocytic leukaemia. LAA was present in detectable amounts in 1% of healthy blood donors. Thus LAA is truly leukaemia associated rather than leukaemia specific. Occurrence of LAA in the serum of a leukaemia patient may signal a serious turn of the disease.
在41%-75%的急性白血病或慢性粒细胞白血病患者中发现血清白血病相关抗原(LAA),但在慢性淋巴细胞白血病患者中只有12%的人发现该抗原。1%的健康献血者血清中可检测到LAA。因此,LAA是真正与白血病相关而非白血病特异性的。白血病患者血清中出现LAA可能预示疾病的严重转变。