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[关节腔内注射可的松]

[Intra-articular injection of cortisone].

作者信息

Hammer M, Schwarz T, Ganser G

机构信息

Klinik für Rheumatologie, St. Josef-Stift, Westtor 7, 48324, Sendenhorst, Deutschland.

出版信息

Z Rheumatol. 2015 Nov;74(9):774-9. doi: 10.1007/s00393-015-1626-x.

DOI:10.1007/s00393-015-1626-x
PMID:26511366
Abstract

Intra-articular injections with glucocorticoids are standard procedures according to therapy guidelines in many rheumatic conditions. There is increasing evidence from clinical trials on the treatment of rheumatoid arthritis that more patients will attain the target of remission using a combination of systemic medication and intra-articular injections with glucocorticoids compared to systemic medication alone. Intra-articular injections with glucocorticoids play an important role in the therapeutic management of pediatric rheumatic diseases. In many countries competency in performing intra-articular injections is among the important skills necessary for certification as a specialist in rheumatology.

摘要

根据许多风湿性疾病的治疗指南,关节内注射糖皮质激素是标准治疗程序。越来越多关于类风湿关节炎治疗的临床试验证据表明,与单独使用全身药物相比,更多患者通过联合使用全身药物和关节内注射糖皮质激素能够达到缓解目标。关节内注射糖皮质激素在儿童风湿性疾病的治疗管理中发挥着重要作用。在许多国家,进行关节内注射的能力是获得风湿病专科医生认证所需的重要技能之一。

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1
[Intra-articular injection of cortisone].[关节腔内注射可的松]
Z Rheumatol. 2015 Nov;74(9):774-9. doi: 10.1007/s00393-015-1626-x.
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[Injection treatment with hyaluronic acid].[透明质酸注射治疗]
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[Indications and contraindications for radiosynoviorthesis].[放射性滑膜切除术的适应证与禁忌证]
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[Intra-articular infiltrations in rheumatology: update].[风湿病学中的关节内注射:最新进展]
Rev Med Suisse. 2016 Jan 13;12(500):90-4.
5
I have rheumatoid arthritis in my knee and have been receiving cortisone injections for several years. I'm concerned that there might be a limit on how many injections I can safely have in a year. Also, how many years can I take these injections?
Duke Med Health News. 2007 Feb;13(2):12.
6
A risk-benefit assessment of intra-articular corticosteroids in rheumatic disorders.风湿性疾病中关节腔内注射皮质类固醇的风险效益评估。
Drug Saf. 1999 Nov;21(5):353-65. doi: 10.2165/00002018-199921050-00002.
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[Conservative local therapy of rheumatological diseases].[风湿性疾病的保守局部治疗]
Z Rheumatol. 2015 Nov;74(9):763. doi: 10.1007/s00393-015-1624-z.
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[Topical therapy with corticosteroids in rheumatology].
Vnitr Lek. 2000 Apr;46(4):243-5.
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Interventional ultrasound: a critical overview on ultrasound-guided injections and biopsies.介入性超声:超声引导下注射和活检的批判性概述。
Clin Exp Rheumatol. 2014 Jan-Feb;32(1 Suppl 80):S78-84. Epub 2014 Feb 17.
10
[EULAR evidence-based recommendations on the management of systemic glucocorticoid therapy in rheumatic diseases].[欧洲抗风湿病联盟关于风湿性疾病全身糖皮质激素治疗管理的循证推荐意见]
Z Rheumatol. 2009 Jun;68(4):349-52. doi: 10.1007/s00393-008-0420-4.

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本文引用的文献

1
The clinical effectiveness of intra-articular corticosteroids for arthritis of the lower limb in juvenile idiopathic arthritis: a systematic review.关节内注射皮质类固醇治疗幼年特发性关节炎下肢关节炎的临床疗效:一项系统评价。
Pediatr Rheumatol Online J. 2014 Jun 11;12:23. doi: 10.1186/1546-0096-12-23. eCollection 2014.
2
Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis.生物制剂改善病情抗风湿药的疗效:一项系统文献回顾,为 2013 年更新的 EULAR 类风湿关节炎管理建议提供信息。
Ann Rheum Dis. 2014 Mar;73(3):516-28. doi: 10.1136/annrheumdis-2013-204577. Epub 2014 Jan 7.
3
Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial.
阿达木单抗联合甲氨蝶呤和关节内曲安奈德治疗早期类风湿关节炎的靶向治疗策略可提高缓解率、功能和生活质量。OPERA 研究:一项由研究者发起的、随机、双盲、平行分组、安慰剂对照试验。
Ann Rheum Dis. 2014 Apr;73(4):654-61. doi: 10.1136/annrheumdis-2012-202735. Epub 2013 Feb 23.
4
Delineating the role of multiple intraarticular corticosteroid injections in the management of juvenile idiopathic arthritis in the biologic era.在生物制剂时代,明确多种关节内皮质类固醇注射在幼年特发性关节炎治疗中的作用。
Arthritis Care Res (Hoboken). 2013 Jul;65(7):1112-20. doi: 10.1002/acr.21947.
5
Long-term results of the FIN-RACo trial; treatment with a combination of traditional disease-modifying anti-rheumatic drugs is an excellent option in early rheumatoid arthritis.FIN-RACo 试验的长期结果;在早期类风湿关节炎中,联合使用传统的疾病修饰抗风湿药物治疗是一个极好的选择。
Clin Exp Rheumatol. 2012 Jul-Aug;30(4 Suppl 73):S27-31. Epub 2012 Oct 16.
6
Infliximab for 6 months added on combination therapy in early rheumatoid arthritis: 2-year results from an investigator-initiated, randomised, double-blind, placebo-controlled study (the NEO-RACo Study).英夫利昔单抗联合早期类风湿关节炎的治疗 6 个月:一项由研究者发起的、随机、双盲、安慰剂对照研究(NEO-RACo 研究)的 2 年结果。
Ann Rheum Dis. 2013 Jun;72(6):851-7. doi: 10.1136/annrheumdis-2012-201365. Epub 2012 Jun 30.
7
American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee.美国风湿病学会 2012 年关于手部、髋部和膝部骨关节炎非药物和药物治疗的建议。
Arthritis Care Res (Hoboken). 2012 Apr;64(4):465-74. doi: 10.1002/acr.21596.
8
Short- and long-term efficacy of intra-articular injections with betamethasone as part of a treat-to-target strategy in early rheumatoid arthritis: impact of joint area, repeated injections, MRI findings, anti-CCP, IgM-RF and CRP.早期类风湿关节炎靶向治疗中关节内注射倍他米松的短期和长期疗效:关节面积、重复注射、MRI 结果、抗 CCP、IgM-RF 和 CRP 的影响。
Ann Rheum Dis. 2012 Jun;71(6):851-6. doi: 10.1136/annrheumdis-2011-200632. Epub 2012 Feb 1.
9
Evidence and consensus based GKJR guidelines for the treatment of juvenile idiopathic arthritis.基于循证和共识的 GKJR 幼年特发性关节炎治疗指南。
Clin Immunol. 2012 Feb;142(2):176-93. doi: 10.1016/j.clim.2011.10.003. Epub 2011 Oct 26.
10
European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies.欧洲抗风湿病联盟治疗银屑病关节炎的药物治疗建议。
Ann Rheum Dis. 2012 Jan;71(1):4-12. doi: 10.1136/annrheumdis-2011-200350. Epub 2011 Sep 27.