一名患有下丘脑综合征的白血病女孩的胰岛素和生长激素分泌情况。
Insulin and growth hormone secretion in a leukaemic girl with hypothalamic syndrome.
作者信息
Schilirò G, Russo A, Sciotto A, Vigo R
出版信息
Acta Paediatr Scand. 1977 Mar;66(2):261-3. doi: 10.1111/j.1651-2227.1977.tb07846.x.
Abstract
The authors report a girl with acute lymphoblastic leukaemia presenting hypothalamic syndrome characterized by meningeal leukaemia, hyperphagia and obesity. Insulin and growth hormone secretion, studied with arginine and insulin stimulation tests, showed a high peak of serum insulin and no response of growth hormone. Insulin and growth hormone responses to these tests reverted to normal after intrathecal methotrexate.
摘要
作者报告了一名患有急性淋巴细胞白血病的女孩，其出现了以脑膜白血病、食欲亢进和肥胖为特征的下丘脑综合征。通过精氨酸和胰岛素刺激试验对胰岛素和生长激素分泌进行研究，结果显示血清胰岛素出现高峰，而生长激素无反应。鞘内注射甲氨蝶呤后，胰岛素和生长激素对这些试验的反应恢复正常。
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