Brunel I, Moreno-Palacios E, De Santiago J, Zapardiel I
Eur J Gynaecol Oncol. 2015;36(5):605-6.
Granular cells tumor (GCT) is a rare tumor that develops on skin and soft tissues. Only 1-2% of these tumors present malignant behavior.
The authors report three cases of GCT and review the management of these tumors.
The first case is a 73-year-old woman who was diagnosed with an atypical GCT. She was treated with local excision and then presented a local recurrence 21 months after the surgery. The other two cases are 60- and 58-year-old women diagnosed with a benign GCT. They were treated with single excision; both patients underwent second surgery due to margin affectation.
Management of GCT is not clear nowadays. The careful selection of patients with poor prognostic factors is very important. Follow-up for early diagnosis of local recurrence and metastases of these tumors is of utmost importance.
颗粒细胞瘤（GCT）是一种发生于皮肤和软组织的罕见肿瘤。这些肿瘤中仅有1-2%表现出恶性行为。
作者报告了3例颗粒细胞瘤病例，并回顾了这些肿瘤的治疗情况。
首例病例为一名73岁女性，被诊断为非典型颗粒细胞瘤。她接受了局部切除治疗，术后21个月出现局部复发。另外两例为60岁和58岁女性，被诊断为良性颗粒细胞瘤。她们接受了单次切除治疗；两名患者均因切缘受累而接受了二次手术。
目前颗粒细胞瘤的治疗方法尚不清楚。仔细筛选具有不良预后因素的患者非常重要。对这些肿瘤进行随访以早期诊断局部复发和转移至关重要。
