Clarke Michelle, Thomas Natalie, Giles Lynne, Marshall Helen
Vaccinology and Immunology Research Trials Unit, Women's and Children's Hospital, North Adelaide, South Australia 5006, Australia; School of Medicine, University of Adelaide, South Australia 5006, Australia; Robinson Research Institute, University of Adelaide, South Australia 5006, Australia.
Previously employed at Vaccinology and Immunology Research Trials Unit, Women's and Children's Hospital, North Adelaide, South Australia 5006, Australia.
Vaccine. 2015 Dec 16;33(51):7337-7343. doi: 10.1016/j.vaccine.2015.10.068. Epub 2015 Oct 26.
Pertussis is a highly virulent vaccine preventable disease that remains a global challenge. This study aimed to assess community knowledge of pertussis infection as well as awareness and uptake of adult pertussis booster vaccine.
A cross-sectional survey was conducted of randomly selected households in South Australia by Computer Assisted Telephone Interviews in 2011. Survey data were weighted to the age, gender and geographical area profile of the population.
From 3124 randomly sampled contactable households, 1967 interviews were conducted (participation rate 63%) with individuals aged 18-93 years, including 608 parents of children aged <18 years. The majority of respondents (97%) had heard of pertussis (whooping cough) and 18% reported that a household member had previously contracted whooping cough infection. Most respondents considered whooping cough to be highly contagious (73%) and severe for infants (89%). Over half (51%) of those surveyed were aware that family members commonly transmit pertussis to infants. Despite high knowledge, pertussis vaccine uptake was low, with only 10% of respondents reporting pertussis vaccination in the previous five years. Whilst 61% of respondents were aware of the availability of an adult pertussis booster vaccine, only 8% (n=154) reported their Family Physician had discussed it with them. If provided free, 77% agreed that they would be more likely to accept a booster pertussis vaccination. Independent predictors of recent pertussis vaccination included higher education, larger household size, perception of greater disease severity for infants and discussion with a Family Physician about pertussis vaccination.
Whilst knowledge regarding transmission and severity of Bordetella pertussis was high, uptake of pertussis vaccination for adults is remarkably low amongst the South Australian community. Improved awareness regarding the availability of a booster pertussis vaccine through Family Physicians and/or provision of funded pertussis vaccination for adults has the potential to improve pertussis vaccine coverage.
百日咳是一种高致病性的可通过疫苗预防的疾病，仍然是一项全球性挑战。本研究旨在评估社区对百日咳感染的了解程度以及对成人百日咳加强疫苗的知晓率和接种率。
2011年，通过计算机辅助电话访谈对南澳大利亚随机抽取的家庭进行了横断面调查。调查数据根据人口的年龄、性别和地理区域分布进行加权。
在3124个随机抽取的可联系家庭中，对18 - 93岁的个体进行了1967次访谈（参与率63%），其中包括608名18岁以下儿童的父母。大多数受访者（97%）听说过百日咳（百日咳），18%报告称家庭成员曾感染过百日咳。大多数受访者认为百日咳具有高度传染性（73%），对婴儿危害严重（89%）。超过一半（51%）的受访者意识到家庭成员通常会将百日咳传染给婴儿。尽管知晓率较高，但百日咳疫苗接种率较低，只有10%的受访者报告在过去五年内接种过百日咳疫苗。虽然61%的受访者知道有成人百日咳加强疫苗，但只有8%（n = 154）报告其家庭医生与他们讨论过该疫苗。如果免费提供，77%的人同意他们更有可能接受百日咳加强疫苗接种。近期百日咳疫苗接种的独立预测因素包括高等教育、家庭规模较大、认为婴儿疾病严重程度更高以及与家庭医生讨论过百日咳疫苗接种。
虽然对百日咳博德特氏菌传播和严重程度的知晓率较高，但南澳大利亚社区中成人百日咳疫苗接种率极低。通过家庭医生提高对百日咳加强疫苗可获得性的认识和/或为成人提供资助的百日咳疫苗接种，有可能提高百日咳疫苗接种覆盖率。
