Emerson Sam R, Rosenkranz Sara K, Rosenkranz Richard R, Kurti Stephanie P, Harms Craig A
1Department of Human Nutrition,212 Justin Hall,Kansas State University,Manhattan,KS 66506,USA.
2Department of Kinesiology,Kansas State University,Manhattan,KS,USA.
Public Health Nutr. 2016 Sep;19(13):2435-40. doi: 10.1017/S1368980015003109. Epub 2015 Oct 30.
The prevalence of asthma is rising, presenting serious public health challenges. Recent data suggest that sugar-sweetened beverage (SSB) consumption plays a role in asthma aetiology. The purpose of the present study was to determine whether SSB consumption is linked to post-exercise airway narrowing (predictor of asthma development) across puberty.
Participants completed pulmonary function tests, physical activity and dietary habit questionnaires, and an exercise test to exhaustion.
Community in Manhattan, Kansas, USA.
We recruited ten boys and ten girls from an original cohort of forty participants tested in our laboratory approximately 5 years prior. Participants were aged 9·7 (sd 0·9) years at baseline and 14·7 (sd 0·9) years at follow-up.
Pre-puberty, boys consumed 6·8 (sd 4·8) servings/week and girls consumed 6·9 (sd 3·7) servings/week, while post-puberty boys consumed 11·5 (sd 5·3) servings/week and girls consumed 7·7 (sd 4·3) servings/week. Using Pearson correlation, SSB consumption was not significantly related to post-exercise airway narrowing at pre-puberty (r=-0·35, P=0·130). In linear regression analyses, SSB consumption was significantly related to post-exercise airway narrowing post-puberty before (standardized β=-0·60, P=0·005) but not after (standardized β=-0·33, P=0·211) adjustment for confounders. Change in SSB consumption from pre- to post-puberty was significantly associated with post-exercise airway narrowing post-puberty (r=-0·61, P=0·010) and change in post-exercise airway narrowing from pre- to post-puberty (r=-0·45, P=0·048) when assessed via Pearson correlations.
These findings suggest a possible link between SSB consumption and asthma development during maturation. Reduced SSB intake may be a possible public health avenue for blunting rising asthma prevalence.
哮喘的患病率正在上升，带来了严峻的公共卫生挑战。近期数据表明，饮用含糖饮料（SSB）在哮喘病因学中起一定作用。本研究的目的是确定饮用SSB是否与青春期后运动诱发的气道狭窄（哮喘发展的预测指标）有关。
参与者完成了肺功能测试、身体活动和饮食习惯问卷以及一项运动至 exhaustion 的测试。
美国堪萨斯州曼哈顿的社区。
我们从大约5年前在我们实验室测试的40名参与者的原始队列中招募了10名男孩和10名女孩。参与者基线时年龄为9.7（标准差0.9）岁，随访时为14.7（标准差0.9）岁。
青春期前，男孩每周饮用6.8（标准差4.8）份，女孩每周饮用6.9（标准差3.7）份；青春期后，男孩每周饮用11.5（标准差5.3）份，女孩每周饮用7.7（标准差4.3）份。使用Pearson相关性分析，青春期前饮用SSB与运动后气道狭窄无显著相关性（r = -0.35，P = 0.130）。在线性回归分析中，在调整混杂因素之前，青春期后饮用SSB与运动后气道狭窄显著相关（标准化β = -0.60，P = 0.005），但调整后则无显著相关性（标准化β = -0.33，P = 0.211）。通过Pearson相关性评估时，青春期前后SSB摄入量的变化与青春期后运动后气道狭窄显著相关（r = -0.61，P = 0.010），以及青春期前后运动后气道狭窄的变化显著相关（r = -0.45，P = 0.048）。
这些发现表明饮用SSB与成熟过程中哮喘发展之间可能存在联系。减少SSB摄入量可能是减缓哮喘患病率上升的一条可能的公共卫生途径。
