Forstmeier V, Sorg H, Kabbani M, Herold C, Altintas M A, Krämer R
Klinik für Unfallchirurgie und Orthopädie, Rekonstruktive und Septische Chirurgie, Sporttraumatologie, Bundeswehrkrankenhaus Ulm, Ulm.
Klinik für Plastische, Rekonstruktive und Ästhetische Chirurgie, Alfried Krupp Krankenhaus, Essen.
Handchir Mikrochir Plast Chir. 2015 Dec;47(6):384-8. doi: 10.1055/s-0035-1555868. Epub 2015 Oct 29.
Cutaneous microcirculation has shown to play a key role in wound healing. Although healing disorders are still one of the most common complications in hand surgery, there still exists a lack of scientific research on possible age-related changes in cutaneous microcirculation at the dorsum of hand.
Cutaneous microcirculation at the dorsum of the hand differs significantly between different age groups.
53 healthy subjects were divided into 2 groups by age (Group A:<40 years, n=31 vs. Group B≥40 years, n=22). All subjects underwent measurement of the microcirculation at the dorsum of the hand with combined laser-Doppler and photo spectrometry.
Cutaneous oxygen saturation was significantly higher in Group A than in Group B (A: 64.7±9.9% vs. B: 58.3±12.6%; p=0,044). In contrast, blood flow velocity was significantly higher in Group B (A: 43±19.6 AU vs. B: 56.7±21.1 AU; p=0.019).
The hypothesis of this study was confirmed. This is the first study to show significant differences of cutaneous microcirculation at the dorsum of the hand within different age groups. Further clinical trials are needed in order to examine if delayed wound healing can be correlated to impaired cutaneous microcirculation at the dorsum of the hand.
皮肤微循环已被证明在伤口愈合中起关键作用。尽管愈合障碍仍是手外科最常见的并发症之一，但对于手背皮肤微循环可能存在的与年龄相关的变化仍缺乏科学研究。
不同年龄组之间手背皮肤微循环存在显著差异。
53名健康受试者按年龄分为2组（A组：<40岁，n = 31；B组：≥40岁，n = 22）。所有受试者均采用激光多普勒和光光谱联合测量手背微循环。
A组皮肤氧饱和度显著高于B组（A组：64.7±9.9% 对B组：58.3±12.6%；p = 0.044）。相反，B组血流速度显著更高（A组：43±19.6 AU对B组：56.7±21.1 AU；p = 0.019）。
本研究假设得到证实。这是第一项表明不同年龄组之间手背皮肤微循环存在显著差异的研究。需要进一步的临床试验来检验伤口愈合延迟是否与手背皮肤微循环受损相关。
