Liu Kai, Meng Jiaxiang, Yang Shuofei, Liu Baochen, Ding Weiwei, Wu Xingjiang, Li Jieshou
Medical School of Nanjing University, Nanjing, 210002 Jiangsu Province P. R. China.
Research Institute of General Surgery, Jinling Hospital, 305 East Zhongshan Road, 210002 Nanjing, Jiangsu China.
World J Emerg Surg. 2015 Oct 29;10:50. doi: 10.1186/s13017-015-0045-2. eCollection 2015.
This study aims to evaluate the clinical outcomes of transcatheter thrombolysis in acute superior mesenteric venous thrombosis (ASMVT) associated with bowel necrosis.
A retrospective study of six patients with ASMVT treated with catheter-directed thrombectomy/thrombolysis and damage control surgery at Jinling Hospital (Nanjing, China) between 2010 and 2013 was conducted. Demographics, past medical history, risk factors, therapeutic methods and effects, mortality, and follow-up of the study population were assessed.
Five of six patients underwent arteriovenous combined thrombolysis, while one patient underwent arterial thrombolysis. All patients required damage control surgery, and four of these patients underwent temporary abdominal closure. All patients survived and were free of recurrence.
Transcatheter thrombectomy/thrombolysis and damage control surgery could help avoid extensive bowel resection, prevent short bowel syndrome and reduce mortality for critically ill patients with acute mesenteric venous thrombosis associated with bowel necrosis.
本研究旨在评估经导管溶栓治疗急性肠系膜上静脉血栓形成（ASMVT）合并肠坏死的临床疗效。
对2010年至2013年期间在金陵医院（中国南京）接受导管直接血栓切除术/溶栓及损伤控制手术治疗的6例ASMVT患者进行回顾性研究。评估研究人群的人口统计学、既往病史、危险因素、治疗方法及效果、死亡率和随访情况。
6例患者中5例行动静脉联合溶栓，1例行动脉溶栓。所有患者均需行损伤控制手术，其中4例患者行临时腹部关闭术。所有患者均存活且无复发。
经导管血栓切除术/溶栓及损伤控制手术有助于避免广泛肠切除，预防短肠综合征，并降低急性肠系膜静脉血栓形成合并肠坏死的危重症患者的死亡率。
