Tekleghiorghis T, Weerdmeester K, van Hemert-Kluitenberg F, Moormann R J M, Dekker A
Central Veterinary Institute (Part of Wageningen UR), Lelystad, The Netherlands.
National Veterinary Laboratory, Ministry of Agriculture, Asmara, Eritrea.
Transbound Emerg Dis. 2017 Jun;64(3):754-763. doi: 10.1111/tbed.12434. Epub 2015 Oct 30.
Information about seroprevalence of foot-and-mouth disease (FMD) and virus serotypes in Eritrea is unavailable, but is very important as it may guide the choice of intervention measures including vaccination to be implemented. We carried out a cross-sectional study from February to June 2011 in Eritrea with a two-stage cluster design, sampling cattle in 155 villages with the objective of determining the seroprevalence of FMD in four administrative regions of the country. We analysed cattle sera (n = 2429) for FMD virus antibodies using the non-structural ELISA (NS ELISA) and virus neutralization test (VNT). The overall seroprevalence was 26% and 30% for the NS ELISA and VNT, respectively. FMD virus serotypes O (14%) and A (11%) were the most prevalent. Gash Barka showed the highest (39%) seroprevalence both in NS ELISA and VNT compared to the other three administrative regions. Strategic FMD virus vaccination with type O and A (matching circulating strains) in combination of zoo-sanitary measures would be the best control option for Eritrea which could be started in areas where the disease is less endemic.
厄立特里亚口蹄疫（FMD）血清流行率及病毒血清型的相关信息尚不可知，但这一信息非常重要，因为它可能会指导包括疫苗接种在内的干预措施的选择。2011年2月至6月，我们在厄立特里亚开展了一项采用两阶段整群设计的横断面研究，对155个村庄的牛进行采样，目的是确定该国四个行政区口蹄疫的血清流行率。我们使用非结构ELISA（NS ELISA）和病毒中和试验（VNT）分析了牛血清（n = 2429）中的口蹄疫病毒抗体。NS ELISA和VNT的总体血清流行率分别为26%和30%。口蹄疫病毒血清型O（14%）和A（11%）最为常见。与其他三个行政区相比，加什巴尔卡地区在NS ELISA和VNT中的血清流行率最高（39%）。对于厄立特里亚来说，采用O型和A型（匹配流行毒株）进行口蹄疫病毒的策略性疫苗接种并结合动物卫生措施，将是最佳的防控选择，可在疾病流行程度较低的地区率先开展。
