Ayala S, Perlaza P, Puig S, Prats E, Vidal-Sicart S
Servei de Medicina Nuclear (CDIC), Hospital Clínic Barcelona, Spain; Servicio de Medicina Nuclear, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
Servei de Medicina Nuclear (CDIC), Hospital Clínic Barcelona, Spain.
Rev Esp Med Nucl Imagen Mol. 2016 Mar-Apr;35(2):124-6. doi: 10.1016/j.remn.2015.08.009. Epub 2015 Oct 27.
We analyze the case of a patient with left periorbital infiltrating basal cell carcinoma treated with surgical excision in October 2010. Surgery included orbital exenteration and reconstruction using skin graft and radiotherapy. In May 2013 a MR imaging showed a mass in the left orbital fossa, suggesting a recurrence in the graft. A basal cell carcinoma recurrence with perineural invasion was confirmed in the biopsy. On (18)F-FDG PET/CT performed, a hypermetabolic activity was observed in the left periorbital area with extension to surrounding sinus and bones. The use of (18)F-FDG PET/CT in patients with advanced basal cell carcinoma has not been fully explored due to the rarity of this entity. This case demonstrates the usefulness of this technique to determine the extent of non-melanocytic recurrent skin tumors, and its value in the staging and treatment control, supporting the incorporation of (18)F-FDG PET/CT in the management of advanced basal cell carcinoma.
我们分析了一名左眶周浸润性基底细胞癌患者的病例，该患者于2010年10月接受了手术切除治疗。手术包括眼眶内容剜除术，并使用皮肤移植和放射治疗进行重建。2013年5月，磁共振成像显示左眼眶窝有一个肿块，提示移植部位复发。活检证实为基底细胞癌复发并伴有神经周围浸润。在进行的（18）F-FDG PET/CT检查中，在左眶周区域观察到高代谢活性，并延伸至周围鼻窦和骨骼。由于晚期基底细胞癌病例罕见，（18）F-FDG PET/CT在这类患者中的应用尚未得到充分探索。本病例证明了该技术在确定非黑素细胞性复发性皮肤肿瘤范围方面的有用性，及其在分期和治疗控制中的价值，支持将（18）F-FDG PET/CT纳入晚期基底细胞癌的管理中。
