Shon Hae-Sook, Choi Hwa Young, Kim Jang Rak, Ryu So Yeon, Lee Youn-Jae, Lee Myeong Jin, Min Hyun Ju, Lee Jun, Song Yeong Jun, Ki Moran
Department of Preventive Medicine, College of Medicine, Inje University, Busan, Korea.
Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.
Clin Mol Hepatol. 2015 Sep;21(3):249-56. doi: 10.3350/cmh.2015.21.3.249. Epub 2015 Sep 30.
BACKGROUND/AIMS: This study compared the prevalence of hepatitis C virus (HCV) infection in the Republic of Korea and estimated the high-risk regions and towns.
National Health Insurance Service data for 8 years from 2005 to 2012 were used. The subjects of the study had visited medical facilities and been diagnosed with or received treatment for acute or chronic HCV as a primary or secondary disease according to ICD-10 codes of B17.1 or B18.2, respectively. Any patient who received treatment for the same disease multiple times during 1 year was counted as one patient in that year. To correct for the effect of the age structure of the population by year and region, the age-adjusted prevalence was calculated using the direct method based on the registered population in 2010.
The overall prevalence of HCV infection among Korean adults (>20 years old) increased from 0.14% in 2005 to 0.18% in 2012. The sex-, age-, and region-adjusted prevalence in 2012 was 0.18%. The prevalence was highest in Busan, Jeonnam, and Gyeongnam, and there were towns with noticeably higher prevalences within these regions: Jindo (0.97%) in Jeonnam, Namhae (0.90%) in Gyeongnam, and Seo-gu (0.86%) in Busan.
The prevalence of HCV infection differs by regions as well as towns in the Republic of Korea, and is highest in Busan, Jeonnam, and Gyeongnam. The reasons for the high prevalence in these specific regions should be identified, since this could help prevent HCV infections in the future. In addition, active surveillance and treatment policies should be introduced to stop any further spread of infection in these high-prevalence regions.
背景/目的：本研究比较了韩国丙型肝炎病毒（HCV）感染的患病率，并估计了高风险地区和城镇。
使用了2005年至2012年8年的国民健康保险服务数据。研究对象曾前往医疗机构就诊，并根据ICD-10编码B17.1或B18.2分别被诊断为患有急性或慢性HCV或作为原发性或继发性疾病接受过治疗。在1年内因同一疾病接受多次治疗的任何患者在该年度计为1名患者。为校正各年份和地区人口年龄结构的影响，采用基于2010年登记人口的直接法计算年龄调整患病率。
韩国成年人（>20岁）中HCV感染的总体患病率从2005年的0.14%升至2012年的0.18%。2012年经性别、年龄和地区调整后的患病率为0.18%。釜山、全南和庆南的患病率最高，且在这些地区内有患病率明显较高的城镇：全南的珍岛（0.97%）、庆南的南海（0.90%）和釜山的西区（0.86%）。
韩国HCV感染的患病率因地区和城镇而异，在釜山、全南和庆南最高。应查明这些特定地区患病率高的原因，因为这有助于未来预防HCV感染。此外，应出台积极的监测和治疗政策，以阻止这些高流行地区感染的进一步传播。
