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Effect of an ambulatory diagnostic and treatment programme in patients with sleep apnoea.门诊诊断和治疗方案对睡眠呼吸暂停患者的影响。
Eur Respir J. 2012 Feb;39(2):305-12. doi: 10.1183/09031936.00013311. Epub 2011 Jun 30.
2
ERS Meeting Report. Metabolic aspects of obstructive sleep apnoea syndrome.ERS 会议报告。阻塞性睡眠呼吸暂停综合征的代谢方面。
Eur Respir Rev. 2009 Jun;18(112):113-24. doi: 10.1183/09059180.00000109.
3
Free fatty acids and the metabolic syndrome in patients with obstructive sleep apnoea.游离脂肪酸与阻塞性睡眠呼吸暂停患者的代谢综合征。
Eur Respir J. 2011 Jun;37(6):1418-23. doi: 10.1183/09031936.00050410. Epub 2010 Dec 22.
4
Adult obstructive sleep apnea/hypopnea syndrome: definitions, risk factors, and pathogenesis.成人阻塞性睡眠呼吸暂停/低通气综合征:定义、危险因素和发病机制。
Clin Chest Med. 2010 Jun;31(2):179-86. doi: 10.1016/j.ccm.2010.02.011.
5
Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults.成人阻塞性睡眠呼吸暂停的评估、管理和长期护理临床指南。
J Clin Sleep Med. 2009 Jun 15;5(3):263-76.
6
Sleep, sleep-disordered breathing and metabolic consequences.睡眠、睡眠呼吸障碍与代谢后果。
Eur Respir J. 2009 Jul;34(1):243-60. doi: 10.1183/09031936.00166808.
7
Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation.阻塞性睡眠呼吸暂停综合征中的心血管疾病:间歇性缺氧和炎症的作用。
Eur Respir J. 2009 May;33(5):1195-205. doi: 10.1183/09031936.00111208.
8
Epidemiology of sleep apnoea/hypopnoea syndrome and sleep-disordered breathing.睡眠呼吸暂停/低通气综合征及睡眠呼吸紊乱的流行病学
Eur Respir J. 2009 Apr;33(4):907-14. doi: 10.1183/09031936.00180108.
9
Sleep apnea as an independent risk factor for all-cause mortality: the Busselton Health Study.睡眠呼吸暂停作为全因死亡率的独立危险因素:巴瑟尔顿健康研究
Sleep. 2008 Aug;31(8):1079-85.
10
Cost-effectiveness of using continuous positive airway pressure in the treatment of severe obstructive sleep apnoea/hypopnoea syndrome in the UK.在英国使用持续气道正压通气治疗重度阻塞性睡眠呼吸暂停/低通气综合征的成本效益
Thorax. 2008 Oct;63(10):860-5. doi: 10.1136/thx.2007.086454. Epub 2008 Apr 11.

将睡眠呼吸暂停作为一个公共卫生问题的现代多维方法。

Modern and multidimensional approach of sleep apneea as a public health problem.

作者信息

Todea Doina, Herescu Andreea

机构信息

Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, Romania. Pneumophthisiology Clinical Hospital, Cluj-Napoca, Romania.

出版信息

Clujul Med. 2013;86(1):10-5. Epub 2013 Feb 4.

PMID:26527907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4462468/
Abstract

The obstructive sleep apnea syndrome (OSAS) is a highly prevalent disorder, associated with recurring episodes of partial or complete upper airway occlusion during sleep, which results in marked sleep disturbance, excessive daytime sleepiness, irritability and morning headache, among other symptoms. Sleep apnea is strongly associated with impaired neuropsychological function and reduced quality of life and social functioning. Daytime sleepiness leads to an increased risk for traffic and industrial accidents. OSAS is also independently associated with several cardiovascular complications: not only systemic hypertension but also ischaemic heart disease and stroke. Identifying patients "at risk" and treating them is very important, but at the same time it is time consuming and expensive. Nevertheless, treatment with continuous positive airway pressure (CPAP) has been shown to improve symptoms and quality of life, decrease traffic accidents and may have a positive effect on cardiovascular morbidity. That is why the economic aspects of sleep apnea and the current legislation are an important issue to discuss and manage, for both the patients and the society they live in.

摘要

阻塞性睡眠呼吸暂停综合征(OSAS)是一种高度流行的疾病,与睡眠期间反复出现的部分或完全上呼吸道阻塞发作有关,这会导致明显的睡眠障碍、日间过度嗜睡、易怒和晨起头痛等症状。睡眠呼吸暂停与神经心理功能受损、生活质量下降和社会功能减退密切相关。日间嗜睡会增加交通事故和工业事故的风险。OSAS还与多种心血管并发症独立相关:不仅包括系统性高血压,还包括缺血性心脏病和中风。识别“高危”患者并对其进行治疗非常重要,但同时这既耗时又昂贵。然而,持续气道正压通气(CPAP)治疗已被证明可改善症状和生活质量,减少交通事故,并且可能对心血管发病率产生积极影响。这就是为什么睡眠呼吸暂停的经济方面以及现行立法对于患者及其所处社会来说都是一个需要讨论和管理的重要问题。