Mao Song Shou, Luo Yanting, Fischer Hans, Buodff Matthew J, Li Dong
From the Los Angeles Biomedical Research Institute (LA BioMed), Torrance, CA.
J Comput Assist Tomogr. 2016 Jan-Feb;40(1):126-30. doi: 10.1097/RCT.0000000000000330.
We aimed to assess accuracy and precision of quantitative computed tomography (QCT) and phantomless in thoracic bone mineral density (BMD) assessment using coronary artery calcium scan (CACS).
A total of 513 subjects underwent CACS with a calibration phantom. The thoracic spine BMD and concentration of calcium hydroxyapatite in phantom rods, as well CT Hounsfield unit of both, were measured. The thoracic BMD and phantom-rods calcium concentration were obtained using phantomless. The accuracy and precision error of QCT and phantomless were compared.
The mean biases from true calcium concentration of phantom rods were 2.9% and 3.8% for the QCT and phantomless, respectively (P < 0.001). The biases of thoracic BMD from QCT by phantomless were 3.8% with a similar precision error in both methods.
The thoracic BMD can be assessed accurately and precisely using QCT and phantomless with a routine CACS.
我们旨在评估使用冠状动脉钙化扫描（CACS）进行胸部骨矿物质密度（BMD）评估时，定量计算机断层扫描（QCT）和无体模方法的准确性和精密度。
共有513名受试者接受了带有校准体模的CACS检查。测量了胸椎骨密度、体模棒中羟基磷灰石的浓度以及两者的CT亨氏单位。使用无体模方法获得胸椎骨密度和体模棒钙浓度。比较了QCT和无体模方法的准确性和精密度误差。
QCT和无体模方法与体模棒真实钙浓度的平均偏差分别为2.9%和3.8%（P < 0.001）。无体模方法与QCT测量的胸椎骨密度偏差为3.8%，两种方法的精密度误差相似。
使用QCT和无体模方法结合常规CACS可以准确、精确地评估胸椎骨密度。
