Naspitz C, Solé D
Bol Med Hosp Infant Mex. 1989 Jan;46(1):22-9.
Five congenital agammaglobulinemic (CA) boys, started their recurrent bacterial infections between the ages of 3-18 months, presenting otitis (4), pneumonias (4), chronic diarrhea (4), meningitis (2), septicemia (2), septic arthritis (1) and urinary infection (1). The gamma globulin fraction was below 0.08 mg/dL in all patients. IgG, IgA, IgM and IgE levels were always below 50 mg/dL, 2 mg/dL, 35 mg/dL and 20 IU/mL, respectively. Secretory IgA was non-detectable in all patients. Total complement levels were normal (3) and the C3 fraction was elevated in 4 patients. The in vitro response of peripheral lymphocytes to PHA was normal in 4 patients, as well as the number of OKT3, OKT4 and OKT8 cells (2).
五名先天性无丙种球蛋白血症（CA）男孩在3至18个月大时开始反复出现细菌感染，表现为中耳炎（4例）、肺炎（4例）、慢性腹泻（4例）、脑膜炎（2例）、败血症（2例）、化脓性关节炎（1例）和尿路感染（1例）。所有患者的丙种球蛋白组分均低于0.08mg/dL。IgG、IgA、IgM和IgE水平始终分别低于50mg/dL、2mg/dL、35mg/dL和20IU/mL。所有患者均未检测到分泌型IgA。3例患者的总补体水平正常，4例患者的C3组分升高。4例患者外周淋巴细胞对PHA的体外反应正常，OKT3、OKT4和OKT8细胞数量也正常（2例）。
