Methodist Sports Medicine, Indianapolis, Indiana, USA.
Center for Diagnostic Imaging, Indianapolis, Indiana, USA.
Orthop J Sports Med. 2013 Jun 24;1(1):2325967113494354. doi: 10.1177/2325967113494354. eCollection 2013 Jan-Jun.
Platelet-rich plasma (PRP) injections have been proposed to hasten soft tissue healing. There is a lack of evidence in the current literature to support their efficacy in elite athletes.
To investigate the effects of the addition of PRP to rehabilitation in the treatment of acute hamstring injuries in professional National Football League (NFL) players and to report the time to return to play.
Case control study.
Ten NFL players with similar hamstring injury patterns were retrospectively divided into 2 groups. The treatment group (PRP; n = 5) was injected with PRP and the control group (non-PRP; n = 5) was not injected; both groups completed a rehabilitation program. The PRP injections were administered under ultrasound guidance with precise localization of the injury site, within 24 to 48 hours of injury. Age, muscle involved, extent of injury, grading, and time to return to play were noted. Descriptive statistics and the exact Wilcoxon rank-sum test were used for data analysis.
The mean age was 23 years (range, 22-27 years) for the PRP group and 26 years (range, 22-28 years) for the non-PRP group (P = .42). The median longitudinal extent of the injury was 14 cm (range, 9-18 cm) in the PRP group and 15 cm (range, 9-16 cm) in the non-PRP group (P = .77). The average transverse extent of the injury in the PRP and non-PRP groups was 4 cm (range, 1.6-6 cm) and 3.5 cm (range, 2-5 cm), respectively, and the respective average anteroposterior extent was 4 cm (range, 1.9-5 cm) and 2.9 cm (range, 1.5-4 cm). The long head of biceps femoris was most commonly involved (4 in each group), with a single tear of the semimembranosus in each group. The median injury classification was grade 2 in both groups. The median time to return to play was 20 days (range,16-30 days) in the PRP group and 17 days (range, 8-81 days) in the non-PRP group (P = .73).
There were no significant differences in recovery from hamstring injury between treatment with PRP and routine rehabilitation. A larger, randomized controlled trial is warranted.
富含血小板的血浆 (PRP) 注射被提议加速软组织愈合。目前文献中缺乏支持其在精英运动员中疗效的证据。
调查在治疗职业国家橄榄球联盟 (NFL) 运动员急性腘绳肌损伤时添加 PRP 对康复的影响，并报告重返赛场的时间。
病例对照研究。
回顾性地将 10 名具有相似腘绳肌损伤模式的 NFL 球员分为 2 组。治疗组（PRP；n = 5）接受 PRP 注射，对照组（非 PRP；n = 5）未接受注射；两组均完成康复计划。PRP 注射在超声引导下进行，精确定位损伤部位，在损伤后 24 至 48 小时内进行。记录年龄、受累肌肉、损伤程度、分级和重返赛场时间。使用描述性统计和确切的 Wilcoxon 秩和检验进行数据分析。
PRP 组的平均年龄为 23 岁（范围，22-27 岁），非 PRP 组为 26 岁（范围，22-28 岁）（P =.42）。PRP 组的损伤纵向中位数为 14 cm（范围，9-18 cm），非 PRP 组为 15 cm（范围，9-16 cm）（P =.77）。PRP 和非 PRP 组的损伤横截面积平均为 4 cm（范围，1.6-6 cm）和 3.5 cm（范围，2-5 cm），各自的前后向平均长度为 4 cm（范围，1.9-5 cm）和 2.9 cm（范围，1.5-4 cm）。最常涉及长头股二头肌（每组 4 例），每组均有单一的半膜肌撕裂。两组的损伤分级中位数均为 2 级。PRP 组的平均重返赛场时间为 20 天（范围，16-30 天），非 PRP 组为 17 天（范围，8-81 天）（P =.73）。
在 PRP 治疗与常规康复治疗之间，腘绳肌损伤的恢复没有明显差异。需要进行更大规模的随机对照试验。
