Desouza Clevio, Shetty Vijay
SAANVI Orthopaedics, Mumbai, India.
Dr L H Hiranandani Hospital, Mumbai, India.
Eur J Orthop Surg Traumatol. 2025 Jun 19;35(1):259. doi: 10.1007/s00590-025-04377-3.
Hamstring injuries are a major cause of time-loss in athletes, often leading to prolonged recovery and high recurrence rates. This randomized controlled trial evaluated the efficacy of ultrasound-guided platelet-rich plasma (PRP) injections in accelerating return to play (RTP) and enhancing radiological healing in grade 2 hamstring injuries.
Sixty athletes with MRI-confirmed grade 2 hamstring injuries were randomized into two groups: PRP plus standard therapy (n = 30) and standard therapy alone (n = 30). All followed a standardized rehabilitation protocol. Primary outcome was time to return to play (TTRTP). Secondary outcomes included MRI healing at 21 days, re-injury rates, and adverse events, with a 2-year follow-up.
The PRP group showed significantly faster RTP (26.4 ± 4.5 vs. 34.2 ± 5.7 days; p < 0.001) and greater MRI healing at 21 days (70% vs. 36.7%; p = 0.003). Re-injury rates were lower in the PRP group (3.3% vs. 16.7%), though not statistically significant (p = 0.09). No adverse events were reported.
Ultrasound-guided PRP injection with standard rehabilitation accelerates return to play and improves radiological healing in acute grade 2 hamstring injuries, representing a safe and promising adjunct in sports injury management.
腘绳肌损伤是运动员缺赛的主要原因，常导致恢复时间延长和复发率高。本随机对照试验评估了超声引导下富血小板血浆（PRP）注射在加速二级腘绳肌损伤运动员重返赛场（RTP）及促进影像学愈合方面的疗效。
60例经MRI确诊为二级腘绳肌损伤的运动员被随机分为两组：PRP联合标准治疗组（n = 30）和单纯标准治疗组（n = 30）。所有患者均遵循标准化康复方案。主要结局指标为重返赛场时间（TTRTP）。次要结局指标包括21天时的MRI愈合情况、再损伤率和不良事件，随访2年。
PRP组的RTP明显更快（26.4±4.5天 vs. 34.2±5.7天；p < 0.001），且21天时的MRI愈合情况更好（70% vs. 36.7%；p = 0.003）。PRP组的再损伤率较低（3.3% vs. 16.7%），但无统计学意义（p = 0.09）。未报告不良事件。
超声引导下PRP注射联合标准康复治疗可加速急性二级腘绳肌损伤运动员的重返赛场，并改善影像学愈合，是运动损伤管理中一种安全且有前景的辅助治疗方法。
