Wyon Matthew A, Wolman Roger, Nevill Alan M, Cloak Ross, Metsios George S, Gould Douglas, Ingham Andrew, Koutedakis Yiannis
*Research Centre for Sport Exercise and Performance, University of Wolverhampton, Walsall, United Kingdom; †National Institute of Dance Medicine and Science, United Kingdom; ‡Department of Rheumatology and Sport and Exercise Medicine, Royal National Orthopaedic Hospital, Stanmore, United Kingdom; §Research Centre for Sport Exercise and Performance, University of Wolverhampton, Walsall, United Kingdom; ¶School of Pharmacy, School of Life Sciences, Aston University, Birmingham, United Kingdom; and ‖Department of Exercise Sciences, University of Thessaly, Trikala, Greece.
Clin J Sport Med. 2016 Jul;26(4):279-84. doi: 10.1097/JSM.0000000000000264.
Indoor athletes have been shown to be prone to vitamin D3 deficiency. The aim of the study was to examine the acute effects of vitamin D supplementation on muscle function using isokinetic dynamometry.
Randomized placebo-controlled, double-blind study.
Institutional.
Adult male white national level judoka athletes (n = 22) who were involved in full-time training. Exclusion criteria were vitamin supplementation, overseas travel to sunny climes, and/or an injury incurred during the last 3 months before testing.
Subjects were randomly allocated to the treatment (150 000IU vitamin D3) or placebo and given blinded supplements by an independent researcher. Participants were tested twice, 8 days apart, on a Monday morning before the start of judo training and after 2 days of rest. A 5 to 7 mL of blood sample was collected followed by isokinetic concentric quadriceps and hamstring muscle function assessments on the right leg at 30 and 200°·s.
Repeated-measures analysis of variance was used to analyze isokinetic muscle force and serum 25(OH)D3. Regression to the mean was used to examine changes in 25(OH)D3 levels over the study period.
The treatment group demonstrated a significant increase in serum 25(OH)D levels (34%, P ≤ 0.001) and muscle strength (13%, P = 0.01) between days 1 and 8. No significant differences were found for the placebo group for the same period.
A single bolus of 150 000IU vitamin D3 had a significant positive effect on serum 25(OH)D levels and muscle function in vitamin D insufficient elite indoor athletes.
Serum 25(OH)D3 levels of indoor athletes should be monitored throughout the year and especially during winter months. Beneficial responses, in muscle strength and serum 25(OH)D3, to 1 dose of vitamin D3 supplementation can be observed within 1 week of ingestion. Muscle strength is linked to serum 25(OH)D levels.
已有研究表明室内运动员容易缺乏维生素D3。本研究旨在使用等速测力法检测补充维生素D对肌肉功能的急性影响。
随机安慰剂对照双盲研究。
机构内。
成年男性白人国家级柔道运动员（n = 22），他们参与全日制训练。排除标准为补充维生素、前往阳光充足地区旅行和/或在测试前最后3个月内受伤。
受试者被随机分配至治疗组（150000IU维生素D3）或安慰剂组，由一名独立研究人员给予盲法补充剂。参与者在柔道训练开始前的周一上午以及休息2天后，相隔8天接受两次测试。采集5至7毫升血样，随后在30和200°·s时对右腿进行等速向心股四头肌和腘绳肌肌肉功能评估。
采用重复测量方差分析来分析等速肌力和血清25(OH)D3。使用均值回归来检查研究期间25(OH)D3水平的变化。
治疗组在第1天和第8天之间血清25(OH)D水平显著升高（34%，P≤0.001），肌肉力量增加（13%，P = 0.01）。同期安慰剂组未发现显著差异。
单次大剂量给予150000IU维生素D3对维生素D不足的精英室内运动员的血清25(OH)D水平和肌肉功能有显著的积极影响。
应全年监测室内运动员的血清25(OH)D3水平，尤其是在冬季月份。摄入1剂维生素D3补充剂后1周内，可观察到肌肉力量和血清25(OH)D3的有益反应。肌肉力量与血清25(OH)D水平相关。
