Kornberg Daniel L, Yannuzzi Nicolas A, Klufas Michael A, DʼAmico Donald J, Orlin Anton, Kiss Szilárd
*Department of Ophthalmology, Weill Cornell Medical College, New York, NY; and †Retina Division, Stein Eye Institute/UCLA Medical Center, Los Angeles, CA.
Retina. 2016 Jun;36(6):1101-10. doi: 10.1097/IAE.0000000000000833.
To evaluate the ability to visualize and document posterior segment pathology through the Boston keratoprosthesis (KPro) using the Optos P200Tx ultra-widefield (UWF) scanning laser ophthalmoscope.
A retrospective chart review was conducted of patients who underwent Boston Type I keratoprosthesis implantation and who subsequently were imaged with an UWF system. Ultra-widefield images were reviewed to evaluate for vitreoretinal pathology and were compared with the clinical examination.
In this series of 10 patients (10 eyes), 100% of vitreoretinal pathology found on clinical examination was detectable using the Optos system. In 4 cases (40%), UWF imaging provided superior detection of pathology compared with the clinical examination by imaging through retroprosthetic membranes (3 cases) and by detection of a retinal detachment (one case). In 1 case (10%), B-scan ultrasonography was needed to characterize vitreoretinal pathology that could not be definitively distinguished on UWF imaging and was difficult to detect on clinical examination. Ultra-widefield imaging detected the following vitreoretinal pathologies in KPro eyes: retinal hemorrhage, epiretinal membrane, retinal detachment, proliferative diabetic retinopathy, and choroidal folds.
Ultra-widefield imaging provides a high-resolution view of the posterior pole and periphery despite the limitations of imaging through the narrow optic of Boston Type I keratoprosthesis, and it may improve visualization through retroprosthetic membranes. Detection and documentation of vitreoretinal complications in the setting of a permanent keratoprosthesis may be enhanced using UWF imaging.
使用Optos P200Tx超广角(UWF)扫描激光检眼镜评估通过波士顿人工角膜(KPro)观察和记录眼后段病变的能力。
对接受波士顿I型人工角膜植入术并随后使用UWF系统进行成像的患者进行回顾性病历审查。回顾超广角图像以评估玻璃体视网膜病变,并与临床检查结果进行比较。
在这组10例患者(10只眼)中,临床检查发现的100%的玻璃体视网膜病变使用Optos系统均可检测到。在4例(40%)患者中,与临床检查相比,UWF成像通过经人工角膜后膜成像(3例)和检测视网膜脱离(1例),对病变的检测效果更佳。在1例(10%)患者中,需要B超检查来明确UWF成像上无法明确区分且临床检查难以检测到的玻璃体视网膜病变特征。超广角成像在KPro眼中检测到以下玻璃体视网膜病变:视网膜出血、视网膜前膜、视网膜脱离、增殖性糖尿病视网膜病变和脉络膜皱褶。
尽管通过波士顿I型人工角膜的狭窄光学部分成像存在局限性,但超广角成像仍能提供后极部和周边的高分辨率视图,并且可能改善经人工角膜后膜的成像效果。使用UWF成像可增强对永久性人工角膜情况下玻璃体视网膜并发症的检测和记录。