一种具有聚集诱导发光特性且对细胞内和细胞外pH变化具有高灵敏度的二氟化硼染料。
A boron difluoride dye showing the aggregation-induced emission feature and high sensitivity to intra- and extra-cellular pH changes.
作者信息
Wu Dan, Shao Li, Li Yang, Hu Qinglian, Huang Feihe, Yu Guocan, Tang Guping
机构信息
Department of Chemistry, Zhejiang University, 310028 Hangzhou, P. R. China.
出版信息
Chem Commun (Camb). 2016 Jan 11;52(3):541-4. doi: 10.1039/c5cc08429f. Epub 2015 Nov 5.
PMID:26537000
Abstract
A novel AIE-active boron difluoride fluorescent probe P3T was designed and synthesized. P3T exhibited high sensitivity to intra- and extra-cellular pH changes. Furthermore, a Förster resonance energy transfer (FRET) system was constructed, where P3T acted as a donor fluorophore and DOX as the acceptor.
摘要
设计并合成了一种新型的具有聚集诱导发光（AIE）活性的二氟化硼荧光探针P3T。P3T对细胞内和细胞外的pH变化表现出高灵敏度。此外，构建了一种荧光共振能量转移（FRET）体系，其中P3T作为供体荧光团，阿霉素（DOX）作为受体。
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