Wu Dan, Shao Li, Li Yang, Hu Qinglian, Huang Feihe, Yu Guocan, Tang Guping
Department of Chemistry, Zhejiang University, 310028 Hangzhou, P. R. China.
Chem Commun (Camb). 2016 Jan 11;52(3):541-4. doi: 10.1039/c5cc08429f. Epub 2015 Nov 5.
A novel AIE-active boron difluoride fluorescent probe P3T was designed and synthesized. P3T exhibited high sensitivity to intra- and extra-cellular pH changes. Furthermore, a Förster resonance energy transfer (FRET) system was constructed, where P3T acted as a donor fluorophore and DOX as the acceptor.
设计并合成了一种新型的具有聚集诱导发光（AIE）活性的二氟化硼荧光探针P3T。P3T对细胞内和细胞外的pH变化表现出高灵敏度。此外，构建了一种荧光共振能量转移（FRET）体系，其中P3T作为供体荧光团，阿霉素（DOX）作为受体。
