Morawetz Carmen, Bode Stefan, Baudewig Juergen, Jacobs Arthur M, Heekeren Hauke R
Department of Education and Psychology, Freie Universität Berlin, Germany.
Melbourne School of Psychological Sciences, the University of Melbourne, Australia.
Hum Brain Mapp. 2016 Feb;37(2):600-20. doi: 10.1002/hbm.23053. Epub 2015 Nov 5.
The use of top-down cognitive control mechanisms to regulate emotional responses as circumstances change is critical for mental and physical health. Several theoretical models of emotion regulation have been postulated; it remains unclear, however, in which brain regions emotion regulation goals (e.g., the downregulation of fear) are represented. Here, we examined the neural mechanisms of regulating emotion using fMRI and identified brain regions representing reappraisal goals. Using a multimethodological analysis approach, combining standard activation-based and pattern-information analyses, we identified a distributed network of lateral frontal, temporal, and parietal regions implicated in reappraisal and within it, a core system that represents reappraisal goals in an abstract, stimulus-independent fashion. Within this core system, the neural pattern-separability in a subset of regions including the left inferior frontal gyrus, middle temporal gyrus, and inferior parietal lobe was related to the success in emotion regulation. Those brain regions might link the prefrontal control regions with the subcortical affective regions. Given the strong association of this subsystem with inner speech functions and semantic memory, we conclude that those cognitive mechanisms may be used for orchestrating emotion regulation. Hum Brain Mapp 37:600-620, 2016. © 2015 Wiley Periodicals, Inc.
随着环境变化，运用自上而下的认知控制机制来调节情绪反应对身心健康至关重要。已经提出了几种情绪调节的理论模型；然而，尚不清楚情绪调节目标（例如，恐惧的下调）在哪些脑区中得到表征。在此，我们使用功能磁共振成像（fMRI）研究了调节情绪的神经机制，并确定了代表重新评估目标的脑区。通过结合基于标准激活和模式信息分析的多方法分析方法，我们确定了一个涉及重新评估的外侧额叶、颞叶和顶叶区域的分布式网络，并且在其中确定了一个以抽象的、与刺激无关的方式代表重新评估目标的核心系统。在这个核心系统内，包括左侧额下回、颞中回和顶下小叶在内的一部分区域中的神经模式可分离性与情绪调节的成功相关。这些脑区可能将前额叶控制区域与皮质下情感区域联系起来。鉴于该子系统与内心言语功能和语义记忆的紧密关联，我们得出结论，这些认知机制可能用于协调情绪调节。《人类大脑图谱》37:600 - 620，2016年。© 2015威利期刊公司。
