Siza Julius E, Kaatano Godfrey M, Chai Jong-Yil, Eom Keeseon S, Rim Han-Jong, Yong Tai-Soon, Min Duk-Young, Chang Su Young, Ko Yunsuk, Changalucha John M
National Institute of Medical Research, P.O. Box 1462, Mwanza, Tanzania.
Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.
Korean J Parasitol. 2015 Oct;53(5):515-24. doi: 10.3347/kjp.2015.53.5.515. Epub 2015 Oct 29.
The objectives of this study was to conduct a survey on schistosomiasis and soil-transmitted helminth (STH) infections in order to come up with feasible control strategies in Lake Victoria basin, Tanzania. Depending on the size of the school, 150-200 schoolchildren were recruited for the study. Duplicate Kato-Katz stool smears were prepared from each child and microscopically examined for Schistosoma mansoni and STHs. Urine specimens were examined for Schistosoma haematobium eggs using the filtration technique. After the survey, mass drug administration was done using praziquantel and albendazole for schistosomiasis and STHs infections, respectively. A total of 5,952 schoolchildren from 36 schools were recruited for the study and had their stool and urine specimens examined. Out of 5,952 schoolchildren, 898 (15.1%) were positive for S. mansoni, 754 (12.6%) for hookworms, 188 (3.2%) for Ascaris lumblicoides, and 5 (0.008%) for Trichuris trichiura. Out of 5,826 schoolchildren who provided urine samples, 519 (8.9%) were positive for S. haematobium eggs. The results revealed that intestinal schistosomiasis, urogenital schistosomiasis, and STH infections are highly prevalent throughought the lake basin. The high prevalence of intestinal and urogenital schistosomisiasis in the study area was a function of the distance from Lake Victoria, the former being more prevalent at localities close to the lake, whilst the latter is more so away from it. Control of schistosomiasis and STHs in the study area requires an integrated strategy that involves provision of health education to communities, regular treatments, and provision of adequate safe water supply and sanitation facilities.
本研究的目的是对坦桑尼亚维多利亚湖流域的血吸虫病和土壤传播的蠕虫(STH)感染情况进行调查,以便制定可行的控制策略。根据学校规模,招募了150 - 200名学童参与研究。从每个孩子身上制备两份Kato-Katz粪便涂片,并进行显微镜检查,以检测曼氏血吸虫和土壤传播的蠕虫。使用过滤技术对尿液标本进行埃及血吸虫卵检测。调查结束后,分别使用吡喹酮和阿苯达唑对血吸虫病和土壤传播的蠕虫感染进行群体药物治疗。共有来自36所学校的5952名学童参与了研究,并对他们的粪便和尿液标本进行了检查。在5952名学童中,898名(15.1%)曼氏血吸虫检测呈阳性,754名(12.6%)钩虫检测呈阳性,188名(3.2%)蛔虫检测呈阳性,5名(0.008%)鞭虫检测呈阳性。在提供尿液样本的5826名学童中,519名(8.9%)埃及血吸虫卵检测呈阳性。结果显示,肠道血吸虫病、泌尿生殖系统血吸虫病和土壤传播的蠕虫感染在整个湖流域都非常普遍。研究区域内肠道和泌尿生殖系统血吸虫病的高流行率与距维多利亚湖的距离有关,前者在靠近湖泊的地区更为普遍,而后者在远离湖泊的地区更为普遍。控制研究区域内的血吸虫病和土壤传播的蠕虫需要采取综合策略,包括向社区提供健康教育、定期治疗以及提供充足的安全供水和卫生设施。