Møller Anne, Reventlow Susanne, Hansen Åse Marie, Andersen Lars L, Siersma Volkert, Lund Rikke, Avlund Kirsten, Andersen Johan Hviid, Mortensen Ole Steen
Department of Occupational Medicine, Copenhagen University Hospital Holbæk, Holbæk, Denmark National Research Centre for the Working Environment, Copenhagen, Denmark Department of Public Health, The Research Unit for General Practice and Section of General Practice, University of Copenhagen, Copenhagen, Denmark.
Department of Public Health, The Research Unit for General Practice and Section of General Practice, University of Copenhagen, Copenhagen, Denmark.
BMJ Open. 2015 Nov 4;5(11):e009873. doi: 10.1136/bmjopen-2015-009873.
Our aim was to study associations between physical exposures throughout working life and physical function measured as chair-rise performance in midlife.
The Copenhagen Aging and Midlife Biobank (CAMB) provided data about employment and measures of physical function. Individual job histories were assigned exposures from a job exposure matrix. Exposures were standardised to ton-years (lifting 1000 kg each day in 1 year), stand-years (standing/walking for 6 h each day in 1 year) and kneel-years (kneeling for 1 h each day in 1 year). The associations between exposure-years and chair-rise performance (number of chair-rises in 30 s) were analysed in multivariate linear and non-linear regression models adjusted for covariates.
Mean age among the 5095 participants was 59 years in both genders, and, on average, men achieved 21.58 (SD=5.60) and women 20.38 (SD=5.33) chair-rises in 30 s. Physical exposures were associated with poorer chair-rise performance in both men and women, however, only associations between lifting and standing/walking and chair-rise remained statistically significant among men in the final model. Spline regression analyses showed non-linear associations and confirmed the findings.
Higher physical exposure throughout working life is associated with slightly poorer chair-rise performance. The associations between exposure and outcome were non-linear.
我们的目的是研究整个工作生涯中的身体暴露与中年时期以从椅子上起身能力衡量的身体功能之间的关联。
哥本哈根衰老与中年生物样本库(CAMB)提供了就业和身体功能测量数据。根据工作暴露矩阵为个人工作经历分配暴露情况。暴露情况被标准化为吨 - 年(1年内每天搬运1000千克)、站立 - 年(1年内每天站立/行走6小时)和跪 - 年(1年内每天跪1小时)。在针对协变量进行调整的多元线性和非线性回归模型中分析暴露年限与从椅子上起身能力(30秒内从椅子上起身的次数)之间的关联。
5095名参与者的平均年龄在两性中均为59岁,平均而言,男性在30秒内可完成21.58次(标准差 = 5.60)从椅子上起身,女性为20.38次(标准差 = 5.33)。身体暴露与男性和女性较差的从椅子上起身能力均相关,然而,在最终模型中,仅搬运以及站立/行走与男性从椅子上起身能力之间的关联仍具有统计学意义。样条回归分析显示了非线性关联并证实了这些发现。
整个工作生涯中较高的身体暴露与稍差的从椅子上起身能力相关。暴露与结果之间的关联是非线性的。