一种β杆状病毒编码的gp64同源物编码一种功能性包膜融合蛋白。
A Betabaculovirus-Encoded gp64 Homolog Codes for a Functional Envelope Fusion Protein.
作者信息
Ardisson-Araújo Daniel M P, Melo Fernando L, Clem Rollie J, Wolff José L C, Ribeiro Bergmann M
机构信息
Laboratory of Baculovirus, Cell Biology Department, University of Brasilia, Brasilia, DF, Brazil Division of Biology, Kansas State University, Manhattan, Kansas, USA.
Laboratory of Baculovirus, Cell Biology Department, University of Brasilia, Brasilia, DF, Brazil.
出版信息
J Virol. 2015 Nov 4;90(3):1668-72. doi: 10.1128/JVI.02491-15. Print 2016 Feb 1.
Abstract
The GP64 envelope fusion protein is a hallmark of group I alphabaculoviruses. However, the Diatraea saccharalis granulovirus genome sequence revealed the first betabaculovirus species harboring a gp64 homolog (disa118). In this work, we have shown that this homolog encodes a functional envelope fusion protein and could enable the infection and fusogenic abilities of a gp64-null prototype baculovirus. Therefore, GP64 may complement or may be in the process of replacing F protein activity in this virus lineage.
摘要
GP64包膜融合蛋白是I组杆状病毒的一个标志。然而，甘蔗条螟颗粒体病毒的基因组序列揭示了首个携带gp64同源物（disa118）的β-杆状病毒物种。在这项研究中，我们已经表明，这个同源物编码一种功能性包膜融合蛋白，并能够赋予一种缺乏gp64的杆状病毒原型感染和融合能力。因此，在这个病毒谱系中，GP64可能补充或可能正在取代F蛋白的活性。
相似文献
1
A Betabaculovirus-Encoded gp64 Homolog Codes for a Functional Envelope Fusion Protein.一种β杆状病毒编码的gp64同源物编码一种功能性包膜融合蛋白。
J Virol. 2015 Nov 4;90(3):1668-72. doi: 10.1128/JVI.02491-15. Print 2016 Feb 1.
2
Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro.将 GP64 并入棉铃虫核多角体病毒可增强病毒在体内和体外的感染力。
J Gen Virol. 2012 Dec;93(Pt 12):2705-2711. doi: 10.1099/vir.0.046458-0. Epub 2012 Sep 5.
3
A betabaculovirus encoding a gp64 homolog.一种编码gp64同源物的β杆状病毒。
BMC Genomics. 2016 Feb 4;17:94. doi: 10.1186/s12864-016-2408-9.
4
A functional F analogue of Autographa californica nucleopolyhedrovirus GP64 from the Agrotis segetum granulovirus.来自黄地老虎颗粒体病毒的一种草地贪夜蛾核多角体病毒GP64的功能性F类似物。
J Virol. 2008 Sep;82(17):8922-6. doi: 10.1128/JVI.00493-08. Epub 2008 Jun 18.
5
Betabaculovirus F proteins showed different efficiencies when rescuing the infectivity of gp64-null Autographa californica nucleopolyhedrovirus.β杆状病毒 F 蛋白在拯救 gp64 缺失型美洲棉铃虫核多角体病毒的感染力方面表现出不同的效率。
Virology. 2013 Feb 5;436(1):59-66. doi: 10.1016/j.virol.2012.10.017. Epub 2012 Dec 13.
6
The Complete Genome Sequence of a Second Distinct Betabaculovirus from the True Armyworm, Mythimna unipuncta.来自粘虫（Mythimna unipuncta）的第二种不同β杆状病毒的全基因组序列
PLoS One. 2017 Jan 19;12(1):e0170510. doi: 10.1371/journal.pone.0170510. eCollection 2017.
7
Unraveling the entry mechanism of baculoviruses and its evolutionary implications.解析杆状病毒的进入机制及其进化意义。
J Virol. 2014 Feb;88(4):2301-11. doi: 10.1128/JVI.03204-13. Epub 2013 Dec 11.
8
A novel baculovirus envelope fusion protein with a proprotein convertase cleavage site.一种具有前蛋白转化酶切割位点的新型杆状病毒包膜融合蛋白。
Virology. 2000 Sep 15;275(1):30-41. doi: 10.1006/viro.2000.0483.
9
Functional role of the cytoplasmic tail domain of the major envelope fusion protein of group II baculoviruses.II组杆状病毒主要包膜融合蛋白细胞质尾域的功能作用
J Virol. 2006 Nov;80(22):11226-34. doi: 10.1128/JVI.01178-06.
10
Transduction of vertebrate cells with Spodoptera exigua multiple nucleopolyhedrovirus F protein-pseudotyped gp64-null Autographa californica multiple nucleopolyhedrovirus.用甜菜夜蛾多核多角体病毒F蛋白假型化的缺失gp64的苜蓿银纹夜蛾多核多角体病毒转导脊椎动物细胞。
J Gen Virol. 2009 Sep;90(Pt 9):2282-7. doi: 10.1099/vir.0.012138-0. Epub 2009 May 27.
引用本文的文献
1
Experimental and evolutionary evidence for horizontal transfer of an envelope fusion protein gene between thogotoviruses and baculoviruses.托高土病毒与杆状病毒之间包膜融合蛋白基因水平转移的实验与进化证据。
J Virol. 2025 Jun 25:e0214824. doi: 10.1128/jvi.02148-24.
2
NezhNPV, a new biocontrol agent for Nesodiprion zhejiangensis Zhou & Xiao (Hymenoptera: Diprionidae), an emerging forest pest.浙江松叶蜂新生物防治剂NezhNPV，浙江松叶蜂（膜翅目：松叶蜂科）是一种新出现的森林害虫。
Pest Manag Sci. 2025 Mar;81(3):1171-1185. doi: 10.1002/ps.8516. Epub 2024 Nov 6.
3
Evaluation of the anti-apoptotic activity of bovine alphaherpesvirus type 5 US3 protein kinase in insect cells using a recombinant baculovirus.利用重组杆状病毒评估牛疱疹病毒 5 型 US3 蛋白激酶在昆虫细胞中的抗凋亡活性。
Braz J Microbiol. 2020 Jun;51(2):827-835. doi: 10.1007/s42770-019-00215-x. Epub 2020 Jan 7.
4
A Nymphalid-Infecting Group I Alphabaculovirus Isolated from the Major Passion Fruit Caterpillar Pest (Lepidoptera: Nymphalidae).从主要百香果鳞翅目害虫（鳞翅目：蛱蝶科）中分离到的一种 Nymphalid 感染组 I Alphabaculovirus
Viruses. 2019 Jul 3;11(7):602. doi: 10.3390/v11070602.
5
Improving Baculovirus Transduction of Mammalian Cells by Incorporation of Thogotovirus Glycoproteins.通过添加 Thogotovirus 糖蛋白提高杆状病毒对哺乳动物细胞的转导效率。
Virol Sin. 2019 Aug;34(4):454-466. doi: 10.1007/s12250-019-00133-0. Epub 2019 Jun 14.
6
Cross-talking between baculoviruses and host insects towards a successful infection.杆状病毒与其宿主昆虫之间的交叉对话有助于成功感染。
Philos Trans R Soc Lond B Biol Sci. 2019 Mar 4;374(1767):20180324. doi: 10.1098/rstb.2018.0324.
7
Genome analysis of a novel Group I alphabaculovirus obtained from Oxyplax ochracea.从赭色尖额蟹中获得的一种新型I组杆状病毒的基因组分析。
PLoS One. 2018 Feb 1;13(2):e0192279. doi: 10.1371/journal.pone.0192279. eCollection 2018.
8
Autographa californica Nucleopolyhedrovirus AC141 (Exon0), a Potential E3 Ubiquitin Ligase, Interacts with Viral Ubiquitin and AC66 To Facilitate Nucleocapsid Egress.苜蓿银纹夜蛾核型多角体病毒AC141（外显子0），一种潜在的E3泛素连接酶，与病毒泛素和AC66相互作用以促进核衣壳出芽。
J Virol. 2018 Jan 17;92(3). doi: 10.1128/JVI.01713-17. Print 2018 Feb 1.
9
A betabaculovirus encoding a gp64 homolog.一种编码gp64同源物的β杆状病毒。
BMC Genomics. 2016 Feb 4;17:94. doi: 10.1186/s12864-016-2408-9.
本文引用的文献
1
Unraveling the entry mechanism of baculoviruses and its evolutionary implications.解析杆状病毒的进入机制及其进化意义。
J Virol. 2014 Feb;88(4):2301-11. doi: 10.1128/JVI.03204-13. Epub 2013 Dec 11.
2
The transcriptome of the baculovirus Autographa californica multiple nucleopolyhedrovirus in Trichoplusia ni cells.棉铃虫细胞中杆状病毒 Autographa californica 多角体病毒的转录组。
J Virol. 2013 Jun;87(11):6391-405. doi: 10.1128/JVI.00194-13. Epub 2013 Mar 27.
3
Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro.将 GP64 并入棉铃虫核多角体病毒可增强病毒在体内和体外的感染力。
J Gen Virol. 2012 Dec;93(Pt 12):2705-2711. doi: 10.1099/vir.0.046458-0. Epub 2012 Sep 5.
4
A single amino acid substitution modulates low-pH-triggered membrane fusion of GP64 protein in Autographa californica and Bombyx mori nucleopolyhedroviruses.一个氨基酸取代突变调节了美洲棉铃虫和家蚕核型多角体病毒 GP64 蛋白在低 pH 值下的膜融合。
Virology. 2010 Sep 1;404(2):204-14. doi: 10.1016/j.virol.2010.04.028.
5
Baculovirus GP64 disulfide bonds: the intermolecular disulfide bond of Autographa californica multicapsid nucleopolyhedrovirus GP64 is not essential for membrane fusion and virion budding.杆状病毒 GP64 二硫键：棉铃虫多核衣壳多角体病毒 GP64 的分子间二硫键对于膜融合和病毒芽殖并非必需。
J Virol. 2010 Sep;84(17):8584-95. doi: 10.1128/JVI.00264-10. Epub 2010 Jun 23.
6
The pre-transmembrane domain of the Autographa californica multicapsid nucleopolyhedrovirus GP64 protein is critical for membrane fusion and virus infectivity.苜蓿银纹夜蛾多核衣壳核多角体病毒GP64蛋白的跨膜前结构域对膜融合和病毒感染性至关重要。
J Virol. 2009 Nov;83(21):10993-1004. doi: 10.1128/JVI.01085-09. Epub 2009 Aug 19.
7
Transduction of vertebrate cells with Spodoptera exigua multiple nucleopolyhedrovirus F protein-pseudotyped gp64-null Autographa californica multiple nucleopolyhedrovirus.用甜菜夜蛾多核多角体病毒F蛋白假型化的缺失gp64的苜蓿银纹夜蛾多核多角体病毒转导脊椎动物细胞。
J Gen Virol. 2009 Sep;90(Pt 9):2282-7. doi: 10.1099/vir.0.012138-0. Epub 2009 May 27.
8
Identification of a GP64 subdomain involved in receptor binding by budded virions of the baculovirus Autographica californica multicapsid nucleopolyhedrovirus.鉴定苜蓿银纹夜蛾多粒包埋核型多角体病毒（Autographica californica multicapsid nucleopolyhedrovirus）出芽病毒粒子中参与受体结合的GP64亚结构域。
J Virol. 2008 May;82(9):4449-60. doi: 10.1128/JVI.02490-07. Epub 2008 Feb 20.
9
Proteomics computational analyses suggest that baculovirus GP64 superfamily proteins are class III penetrenes.蛋白质组学计算分析表明杆状病毒GP64超家族蛋白是III类穿透素。
Virol J. 2008 Feb 18;5:28. doi: 10.1186/1743-422X-5-28.
10
Mapping the conformational epitope of a neutralizing antibody (AcV1) directed against the AcMNPV GP64 protein.绘制针对苜蓿银纹夜蛾核型多角体病毒GP64蛋白的中和抗体（AcV1）的构象表位图谱。
Virology. 2006 Sep 1;352(2):427-37. doi: 10.1016/j.virol.2006.04.041. Epub 2006 Jun 14.
Zotero 插件