一匹马患获得性多重酰基辅酶A脱氢酶缺乏症并伴有明显硒缺乏，导致严重横纹肌溶解。
Acquired multiple acyl-CoA dehydrogenase deficiency and marked selenium deficiency causing severe rhabdomyolysis in a horse.
作者信息
Gomez Diego E, Valberg Stephanie J, Magdesian K Gary, Hanna Paul E, Lofstedt Jeanne
机构信息
Department of Health Management (Gomez, Lofstedt) and Department of Pathology and Microbiology (Hanna), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA (Valberg); Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Shields Avenue, Davis, California 95616, USA (Magdesian).
出版信息
Can Vet J. 2015 Nov;56(11):1166-71.
Abstract
This report describes a case of severe rhabdomyolysis in a pregnant mare associated with histopathologic and biochemical features of both selenium deficiency and acquired multiple acyl-CoA dehydrogenase deficiency (MADD) due to seasonal pasture myopathy (SPM). This case highlights the importance of assessing plasma selenium levels in horses with clinical signs of pasture myopathy as this deficiency may be a contributing or exacerbating factor.
摘要
本报告描述了一例怀孕母马发生严重横纹肌溶解症的病例，该病例伴有因季节性牧场肌病（SPM）导致的硒缺乏和后天性多种酰基辅酶A脱氢酶缺乏症（MADD）的组织病理学和生化特征。该病例突出了对出现牧场肌病临床症状的马匹评估血浆硒水平的重要性，因为这种缺乏可能是一个促成或加剧因素。
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