Singh Ajit, Gupta Lalit Kumar, Khare Ashok Kumar, Mittal Asit, Kuldeep C M, Balai Manisha
Department of Dermatology, Venereology and Leprology, R.N.T. Medical College, Udaipur, Rajasthan, India.
Indian J Dermatol. 2015 Sep-Oct;60(5):479-84. doi: 10.4103/0019-5154.164368.
The spectrum of pyoderma changes constantly, and so does the antibiotic susceptibility pattern.
This study was done to assess the magnitude and clinical patterns of pyodermas, their causative micro-organisms, and the antibiotic susceptibility patterns.
Five hundred consecutive, clinically diagnosed and untreated cases of pyoderma, attending the Dermatology OPD of RNT Medical College and MB Government Hospital, Udaipur, from October 2010 to September 2011 were the subjects of this study. A detailed clinical examination, and relevant investigations including bacterial culture and sensitivity, were carried out and recorded.
For statistical analysis of data, the software 'EPI-INFO Version 6' was used, and Chi-square (χ(2)) test was applied.
Of 19576 cases attending skin OPD during the study period, pyoderma was seen in 500 patients; the incidence being 2.55%. Males outnumbered females. The highest number of cases (109; 21.8%) was observed in 1st decade. Lower extremities were the commonest site of predilection. Primary pyodermas outnumbered secondary pyodermas. Furuncle (136; 27.2%) and infectious eczematoid dermatitis (62; 12.4%) were the commonest entities among primary and secondary pyoderma respectively. Staphylococcus aureus was the commonest causative agent in both primary and secondary pyoderma. It showed high susceptibility to amoxycillin + sulbactam, aminoglycosides and cefoperazone, moderate susceptibility to linezolid, while low susceptibility to fluoroquinolones and cephalexin.
Such studies help to assess the changing trend of bacterial infections, their causative organisms and antibiotic susceptibility pattern.
脓疱病的种类不断变化,抗生素敏感性模式亦是如此。
本研究旨在评估脓疱病的严重程度和临床模式、其致病微生物以及抗生素敏感性模式。
2010年10月至2011年9月期间,连续500例临床诊断且未经治疗的脓疱病患者,前往乌代布尔RNT医学院和MB政府医院皮肤科门诊就诊,作为本研究对象。进行了详细的临床检查以及包括细菌培养和药敏试验在内的相关检查并记录。
为进行数据的统计分析,使用了“EPI-INFO 6.0版”软件,并应用了卡方(χ(2))检验。
在研究期间,19576例前往皮肤科门诊就诊的患者中,有500例患有脓疱病,发病率为2.55%。男性多于女性。在第一个十年中观察到的病例数最多(109例;21.8%)。下肢是最常见的好发部位。原发性脓疱病多于继发性脓疱病。疖(136例;27.2%)和感染性湿疹样皮炎(62例;12.4%)分别是原发性和继发性脓疱病中最常见的类型。金黄色葡萄球菌是原发性和继发性脓疱病中最常见的病原体。它对阿莫西林+舒巴坦、氨基糖苷类和头孢哌酮高度敏感,对利奈唑胺中度敏感,而对氟喹诺酮类和头孢氨苄低度敏感。
此类研究有助于评估细菌感染、其致病生物以及抗生素敏感性模式的变化趋势。